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Open Journal of Immunology (OJI) is an international journal dedicated to the latest advancements in immunology. The goal of this journal is to provide a platform for scientists and academicians all over the world to promote, share, and discuss various new issues and developments in different areas of immunology. All…
Tiffany R. Allison, Joshua C. Wright, Gene M. Scalarone
In Trial 1, 19 lots of Blastomyces dermatitidis (T-58; Tennessee dog isolate) were assayed to determine the stability of the reagents following storage. The reactivity of the antigens, produced from 1989 to 2012 and stored at 4°C, was determined by comparing…
Liang Chen, Chen Cheng, Chunxia Zhang, Qin Yao, Ermi Zhao
Ubiquitin-proteasome pathway (UPP) is a significant way of protein degradation and modification in eukaryotic cell and involved in a complex series of intracellular processes. As a key component in UPP, ubiquitin-conjugating enzyme (E2) plays an extremely imp…
V. Wallace McCarlie, James K. Hartsfield Jr, Janice S. Blum, Carlos González-Cabezas, Judith R. Chin, George J. Eckert, Lorri A. Morford, Mark D. Pescovitz, Henry Rodriguez, Margherita Fontana, Richard L. Gregory
Bacterial adherence to the acquired dental pellicle, important in dental caries (caries), is mediated by receptor-adhesins such as salivary agglutinin binding to Streptococcus mutans antigen I/II (I/II). Ten selected I/II epitopes were chosen to determine the…
Monique C. da Silva, Elena B. Lasunskaia, Wilmar Dias da Silva
The cellular immune response elicited by My cobacterium bovis Bacille Calmette-Guérin (BCG) has been carefully investigated, but the humoral immune response has been partially neglected. BALB/c mice were immunized with BCG strain used to immunize humans. Anti…
Masaomi Obata, Takuma Fujii, Mareki Ohtsuji, Yo Kodera, Hiroyuki Nishimura
It has long been known that protein antigen conjugated with polyethylene glycol (PEG), a nonimmunogenic artificial polymer, induces immune tolerance of antigen-specific Th cells. However, the mechanism of this tolerance induction remains unknown. In this stud…
Sergey N. Rumyantsev
According to the xenogamous paradigm of cancer origin, pathogenesis and epidemic spread, human cancer is a disease caused by the appearance in the afflicted body of deviant multicellular structures whose cells are aggressive (gobble the afflicted body; grow a…
Mohammad Ehlayel, Abdulbari Bener, Mohammad Abu Laban
Background: The high consanguinity in Middle East increases the risk of genetic diseases, including primary immunodeficiency diseases (PID). Objectives: This study was aimed at determining the rate of positive family history of PID, the overall rate and type…
Kota Moriguchi, Katsuichi Miyamoto, Juri Ichihashi, Susumu Kusunoki
In this study, we investigated the clinical relevance of anti-myelin antibodies in patients with neuromyelitis optica (NMO); titers of antibodies against myelin oligodendrocyte glycoproteins, proteolipid proteins and myelin basic proteins were measured in the…
Sylwia M. Slotwinska
The course and severity of periodontitis can be significantly affected by bacterial virulence as well as host immunity dysfunction. Periodontal tissue destruction has been proved to result from cascade of cytokines synthesized by reactive cells upon stimulati…
Siamak Shiva, Farzad Ilkhchooyi, Azim Rezamand
Introduction: Studies that have investigated autoimmune thyroid disease in newly diagnosed type 1 diabetic children are few and reported prevalence rate ranges between 4.5 - 29.4 per cent. Considering the effect of age, ethnic origin, and disease duration on…
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Open Journal of Immunology (OJI) is an international journal dedicated to the latest advancements in immunology. The goal of this journal is to provide a platform for scientists and academicians all over the world to promote, share, and discuss various new issues and developments in different areas of immunology. All… All articles are open access under a CC BY 4.0 licence, with authors retaining copyright.
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