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Open Journal of Immunology (OJI) is an international journal dedicated to the latest advancements in immunology. The goal of this journal is to provide a platform for scientists and academicians all over the world to promote, share, and discuss various new issues and developments in different areas of immunology. All…
Sharada R. Kankonkar, S. V. Joshi, R. R. Deshpande
In India, GI tract cancer is one of the ten leading cancers. Among Indian males it stands second to oral cancer and in females, it shares the third place. Most common malignant disorder of GIT is seen in our country that of liver, bile, gall bladder, pancreas…
Susanne B. Rasmussen, Michael Kosicki, Signe G. Svendsen, Mogens H. Claesson, Nanna N. Kristensen
B7-H4 has been shown to inhibit T cell proliferation, cytokine production and cell cycle in vitro . B7-H4 deficient mice develop exacerbated disease in the mouse models of Rheumatoid Arthritis (RA), Type 1 Diabetes (T1D) and Experimental Autoimmune Encephalom…
Luis A. Salazar, Xóchitl García-Samper, Susana Alcázar-Leyva, Patricia Gorocica, Eduarda Cerón, María Cristina Negrete-García, Luis F. Montaño, Noé Alvarado-Vásquez
Background: Previous evidences support to inflammatory process associated with the IR those important factors in the development of fibrosis and hepatic damage in patients with HCV infection. Objectives: Determine the presence of im munological or histologica…
Zi Yan Tan, Alvin K. L. Khah, Siew Hoon Sim, Vidhya Novem, Yichun Liu, Gek-Yen Gladys Tan
Melioidosis, an infection caused by Gram-negative Burkholderia pseudomallei (Bp), has high clinical recurrence and mortality rates associated with pneumonia and sepsis. With the limitations in current therapeutic options and the lack of available human vaccin…
Monika Palacios-Martínez, María Cristina González-Torres, Leonor Rodríguez-Cruz, Rubén D. Martínez-Pérez, Consuelo del Carmen Cortés-Bejar, Fernando Valencia-Chavarria, Daniel Martínez-Gómez, Oralia Nájera-Medina
Infections in infants and children under five years of age are a public health in México and are one of the major causes of death. Methods In this study, lymphocyte immunophenotyping for CD3+ (T-cells), CD3+CD4+, CD3+CD8+, CD3+CD19+, CD3+CD16/56+, CD45RA+, CD…
Omu Anzala, Gaudensia Nzembi Mutua, Fredrick Jack Odia Oyugi, Bashir Farah Mohamed, Thomas Achia, John Stover
Objective : To estimate the potential impact of an HIV/AIDS Vaccine in Kenya. Design : The Kenyan HIV/AIDS epidemic was modeled using the most current data from national sources including epidemiology and behavioral surveillance. The model’s baseline projecti…
Adriana Catalli, Clayton MacDonald, Priyanka Pundir, Marianna Kulka
Resveratrol, a polyphenol abundant in peanuts, red wine and the skin of grapes, has been shown to have anti-cancer, anti-oxidant and anti-inflammatory activities, and may also have beneficial effects on allergic inflammation. We investigated the effects of re…
Ismat Khatri, Ivo Boudakov, Brent Lamptey, Adriana Taseva, Karrie Wong, Anna Podnos, Reginald M. Gorczynski
CD200:CD200R interactions regulate immune responses. Since CD200Rs show extensive homology in their extracellular region, generating anti-CD200R specific antibodies is a challenge. We report below on the generation of mAbs specific for murine (m)R1/R2 and evi…
Tristan Galbas, Jacques Thibodeau
Membrane-associated RING-CH-1 (MARCH1) is an E3 ubiquitin ligase which targets MHC-II, CD86 and various other molecules for degradation. It is one of the most efficient post-translational regulators of antigen presentation. MARCH1 is expressed in resting imma…
Jun Tanaka, Kumiko Hirano, Yuzuru Sakamoto, Akiko Sugahara-Tobinai, Shota Endo, Yumi Ito-Matsuoka, Atsushi Nakano, Masanori Inui, Lars Nitschke, Toshiyuki Takai
A therapeutic preparation of polyclonal human IgG, i.e. , intravenous immunoglobulin (IVIg), has been employed to treat several inflammatory and autoimmune disorders. B cells are supposed to be a target of IVIg, but the molecular mechanism is elusive because…
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Open Journal of Immunology (OJI) is an international journal dedicated to the latest advancements in immunology. The goal of this journal is to provide a platform for scientists and academicians all over the world to promote, share, and discuss various new issues and developments in different areas of immunology. All… All articles are open access under a CC BY 4.0 licence, with authors retaining copyright.
Authors submit their manuscript, metadata, and declarations through the portal. There is no submission fee.
The editorial office screens the manuscript for scope, completeness, and formatting before assigning a handling editor.
At least two independent reviewers evaluate the manuscript under single-blind review. Where revisions are required, authors respond point by point.
On acceptance the article processing charge is invoiced and the CC BY 4.0 copyright handover is signed.
The article is copyedited, typeset, and given a DOI, then publishes open access with a permanent link.
Manuscripts must be original and not under consideration elsewhere. Submit in Microsoft Word or LaTeX with figures at 300 dpi minimum. Structure research articles as Abstract, Introduction, Methods, Results, Discussion, and References.
Use the journal's numbered (Vancouver) reference style. Cite sources consecutively in the order they appear, and ensure every reference is complete and retrievable.
Declare all funding sources, conflicts of interest, and ethical approvals (including informed consent and animal-care statements where applicable).