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Open Journal of Immunology (OJI) is an international journal dedicated to the latest advancements in immunology. The goal of this journal is to provide a platform for scientists and academicians all over the world to promote, share, and discuss various new issues and developments in different areas of immunology. All…
Mohammed Mehdi, M. K. C. Menon
The role of SNARE [soluble NSF (N-ethylmaleimide-sensitive factor) accessory protein receptor] protein in cellular trafficking, membrane fusion and vesicle release in synaptic nerve terminals is described. The purpose of this review is to highlight the role o…
Gebrehiwot Gebretsadik, M. K. C. Menon
Although the proteomics and its applications in detecting autoimmune diseases are a prominently discussed issue, this review will focus particularly some prominent aspects regarding clinical utility of these techniques in prognosis, diagnosis, and treatment o…
Ziwei Zhu, 1 1, Linxiong Wu, Aihua Liu, 1 1, 1 1, 1 1, 1 1, Mei Zhou, Fukai Bao, 1 1, 1 1, 1 1, 1 1, Cuiping Xu, 1 1, Jiaru Yang, 1 1, Hua Zhao, 1 1, 1 1
Train drivers are engaged in high-stress job. It may induce sleep, fatigue, and alertness loss at work, and endanger public safety. It’s unclear that cytokines of train driver would be influenced by their job. The research considers the hypothesis that stress…
Abdul-Rahman Mubarak, Irene Sitsofe Blebu, Kareem Mumuni, Yao Tettey, Richard Kwasi Gyasi, Andrew Anthony Adjei, Michael Ofori
Introduction: Human leukocyte antigen G (HLA-G) is a non-classical major histocompatibility complex (MHC) class Ib antigen characterized by a limited polymorphism. The expression of HLA-G at immune privileged sites and its ability to inhibit the effectors fun…
Jim M. Banda, Geoffrey C. Onyemelukwe, Bolanle O. P. Musa, Oladapo S. Shittu, Zulai A. Sarkin-Pawa, Aliyu A. Babadoko, Aisha I. Mamman, Adamu G. Bakari, Suraj Junaid
This was a comparative cross-sectional study of eclamptic and normal healthy pregnant women conducted in kaduna State, Nigeria to determine Pregnancy Specific beta-1 Glycoprotein (PSG-1) levels in the peripheral blood of third trimester women with eclampsia (…
Behrouz Moemeni, 1 1, Nathalie Vacaresse, Marina Vainder, Michael E. Wortzman, Tania H. Watts, André Veillette, Thomas F. Gajewski, Michael Julius, 1 1
Genomic disruption of Fyn has not been associated with an immune-deficient phenotype, notwithstanding the profound impairment in IL-2 production by T cells derived from Fyn-deficient animals observed in vitro . The results presented demonstrate that Fyn defic…
Mauro Giacomelli, 1 1, Rajesh Kumar, 1 1, Giacomo Tampella, 1 1, Simona Ceffa, Mario Bontempelli
Idiopathic membranous nephropathy (IMN) is a Th2 nephritogenic immune disorder. It is caused by the accumulation of immune complexes, mainly IgG4, at the basal glomerular membrane that leads to the damage of the glomerular barrier and subsequent injury of pod…
Mohamed M. Hassan, 1 1, Sofia B. Mohamed, Mohamed A. Hussain, Amar A. Dowd
Renal transplantation provides the best long-term treatment for chronic renal failure. Single-nucleotide polymorphisms (SNPs) play a major role in the understanding of the genetic basis of many complex human diseases. Also, the genetics of human phenotype var…
Sarah Moodad, Nayla Al-Akl, Joseph Simaan, Alexander M. Abdelnoor
Previous studies showed that endogenous adenosine, an anti-inflammatory agent, was released at sites of injury and inflammation thereby decreasing the excessive production of pro-inflammatory cytokines. Caffeine, a non-specific adenosine blocker, has been rep…
Nobuo Yamaguchi, Matsuo Arai, Tsugiya Murayama
According to the reports from Ministry of Health in each country, the average life span is elongated over the past decade. This trend is expected to be keeping constant further in the future and at the same time continued efforts should be made. Next, it is n…
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Open Journal of Immunology (OJI) is an international journal dedicated to the latest advancements in immunology. The goal of this journal is to provide a platform for scientists and academicians all over the world to promote, share, and discuss various new issues and developments in different areas of immunology. All… All articles are open access under a CC BY 4.0 licence, with authors retaining copyright.
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