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Pharmacology & Pharmacy is a peer reviewed international journal dedicated to the latest advancements in Pharmacology & Pharmacy. The goal of this journal is to keep a record of the state-of-the-art research and to promote study, research and improvement within its various specialties. All manuscripts submitted to PP…
Wanhui Sheng, 1 1, Robert B. Raffa, 1 1
Planarians have mammalian-like neurotransmitter systems and have been established as a novel in vivo model for neuropharmacology. In previous research, planarians that have been exposed to the cannabinoid receptor (CB-R) agonist WIN 55,212-2 for 1 h displayed…
Yasuhiro Kamioka, Hitoshi Suzuki, Masafumi Seki, Ryusuke Ouchi, Shota Kashiwagura, Satoshi Koshika, Yoshiteru Watanabe
Background : Due to the relatively high renal toxicity of vancomycin injection (VCM), setting an initial dose that achieves a trough that ranges between 10 and 20 μg/mL on day 3 is important to ensure safety and minimize side-effects, especially for patients…
Srinivas Nalamachu, Joseph V. Pergolizzi Jr., Robert Taylor Jr., Jo Ann Le Quang, Joseph V. Pergolizzi III, Robert B. Raffa, 1 1
Opioids are a treatment option for a variety of chronic pain conditions. But long-term opioid use can be associated with side effects, including hypogonadism. Opioid-induced hypogonadism (OIhG) is associated with the alteration of the hypothalamic-pituitary-g…
Sabarni Sarker, Md. Ashraf Ali, Ranjan Kumar Barman, Shuji Noguchi, Yasunori Iwao, Shigeru Itai, Mir Imam Ibne Wahed
The use of Nifedipine (NI), a dihydropyridine calcium channel blocker , is limited due to its poor aqueous solubility. However, NI loaded solid-lipid nanoparticles (NI-SLN) are known to exhibit suitable pharmacokinetic properties and good biocompatibility. Th…
Sumiyo Umeda, Hitomi Yanaguimoto, Seiichi Furuta, Nahoko Kurosawa
We surveyed the drug information retrieval practices among community pharmacists in more rural Hokkaido and in entire Japan in order to explore local characteristics of work-related issues, how community pharmacists access information to address such issues,…
Robert B. Raffa, 1 1, 1 1, Joseph V. Pergolizzi, Robert Taylor
The first “ deuterated ” drug has recently been approved by the U.S. FDA (Food & Drug Administration). A “ deuterated ” drug is a drug in which the hydrogen atom in one or more of the carbon-hydrogen bonds in its chemical structure is replaced by deuterium (…
Galina Sukoyan, Edisher Tsivtsivadze, Veronika Golovach, Tamara Kezeli, Natalya Demina
The aim of the study was to evaluate the efficacy of 2% Cynara scolymus L. extracts in reverse disturbances of collagen metabolism and inflammation in D-galactose induced skin aging model in rats. D-galactose induced aging reproduced in 48 animals of main gro…
Emma F. Bend, Pierre C. Oundoum Oundoum, Marie I. Ngaha Njila, Brice L. Koloko, Camille D. Nyonseu, Samuel H. Mandengue, Paul Moundipa, Theophile Dimo, Dieudonne Massoma Lembè
The aim of the study was to bring scientific evidence of the curative action of the stem bark aqueous extract of Schumanniophyton magnificum (ASMa) on the sexual maturation and fertility of the immature female Wistar rat. Forty immature female rats were rando…
Md. Shahin Sarker, Ranjan Kumar Barman, Md. Ashraf Ali, Shuji Noguchi, Yasunori Iwao, Shigeru Itai, Mir Imam Ibne Wahed
Atorvastatin calcium ( ATV) is a selective competitive inhibitor of HMG CoA reductase characterized by poor aqueous solubility leading to inadequate bioavailability. The present study was designed to develop solid dispersion of atorvastatin (SDA) to improve t…
Laura Cuzzolin, Rocco Agostino
Aim: To analyse antibiotic prescriptions in a cohort of extremely low birth weight neonates admitted to Italian level III Neonatal intensive Care Units. Methods: An online questionnaire was used to collect detailed information for each newborn. Antibiotic pre…
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Pharmacology & Pharmacy is a peer reviewed international journal dedicated to the latest advancements in Pharmacology & Pharmacy. The goal of this journal is to keep a record of the state-of-the-art research and to promote study, research and improvement within its various specialties. All manuscripts submitted to PP… All articles are open access under a CC BY 4.0 licence, with authors retaining copyright.
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