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Pharmacology & Pharmacy is a peer reviewed international journal dedicated to the latest advancements in Pharmacology & Pharmacy. The goal of this journal is to keep a record of the state-of-the-art research and to promote study, research and improvement within its various specialties. All manuscripts submitted to PP…
Muhammad Ali Rajput, Rafeeq Alam Khan, Tahira Assad
Recently use of herbal therapies and diet rich in flavonoids and vitamins has augmented significantly to manage minor to modest illnesses. Several anti-hyperlipidemic agents are currently available; however most of them have various unwanted effects. That’s w…
Mohammed A. Almalki
The risk created by infectious microorganisms to humans attracted the development of common medicine. To find an alternative source, medicinal plants with diverse metabolites play an important role in curing the diseases and human disorders caused by microbia…
Daisuke Chino, Mai Naramatsu, Keisuke Obara, Yoshio Tanaka
Clonidine is a classically categorized α2-adrenoceptor (α 2 -AR) agonist that produces vascular contractions by stimulating arterial smooth muscle α 2 -ARs. However, clonidine inhibits α 1 -AR-mediated arterial contractions. Recently, it was suggested that re…
Tsuyoshi Shirakawa, 1 1, Tomoko Hara, Kojiro Hata, Kojiro Hata, Kimitaka Suetsugu, Hideki Kakimoto, Kentaro Ogata, Yousuke Ikari, Hidenori Sasaki, Makoto Takahashi, Masaru Fukahori, Miyuki Uoi, Taito Esaki, Mikako Hiraike, Toshinobu Hayashi, Akira Tokunaga, Norio Ureshino, Tsuneo Kuwamura, Hitoshi Kusaba, Kenji Mitsugi, Eishi Baba
[Background] Medical staff have many occasions to be exposed to anticancer drugs (ACDs) in the process of performing cancer chemotherapy. Although guidelines for the safe handling of ACDs have been published, actual measures against exposure to ACDs differ be…
Yoshiyuki Hattori, Yuki Yoshiike, Maho Honda, Hiroaki Ohno, Hiraku Onishi
Successful gene silencing by small interfering RNA (siRNA) requires efficient uptake of siRNA into targeted cells. For in vitro transfection of siRNA using cationic liposomes, two types of transfection method are currently being used: conventional (forward; F…
Abdullah Zehad, Gazi Jahirul Islam, Mamunur Rashid, Nusrat Jahan Juthy, Shaheda Zannah
This present study was aimed to investigate the antidiabetic and antihyperlipidemic activities of methanolic leaf extract (LE) of Stephania japonica alone and in combination with metformin in alloxan induced diabetic rats. Primarily acute toxicity study and o…
Veronica Varney, David Salisbury, Helen Parnell, Siva Ratnatheepan, Alex Nicholas, Ginny Quirke, Nazira Sumar, Amolak Bansal
Introduction: In cases of idiopathic pulmonary fibrosis, we have observed an elevation in mean red cell volume, serum gamma glutamyl transferase and peripheral monocyte counts, initially in a pilot study but also in new incident cases. These changes could not…
Brittney V. Hinton, Dolapo A. Adedeji, Gloria E. Payne
Prostate cancer is one of the diseases worldwide that causes cancer-related deaths in men. Metformin is an antidiabetic drug that has been in use for over two decades for the treatment of Type II Diabetes mellitus (DM2). The purpose of this study was to evalu…
Mary Geitona, Aikaterini Toska, Dimitra Latsou, Maria Saridi, Andri Evripidou, Iliada Evripidou
Background: The inappropriate, irrational use or misuse of antibiotics is observed in all health systems and in all patients’ groups worldwide, especially for children, where antibiotics continue to be the drugs most commonly prescribed. Methods: A cross-sect…
Mitsumasa Matsuda, Masanobu Yoshikawa, Takugi Kan, Mariko Watanabe, Junko Ajimi, Shigeru Takahashi, Masaaki Miura, Kenji Ito, Hiroyuki Kobayashi, Toshiyasu Suzuki
Our group has earlier demonstrated that three enzymes sensitive to peptidase inhibitors (PIs), amastatin (A)-, captopril (C)-, and phosphoramidon (P), played an important role in inactivation of enkephalins at the spinal level. Dynorphin-converting enzyme (DC…
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Pharmacology & Pharmacy is a peer reviewed international journal dedicated to the latest advancements in Pharmacology & Pharmacy. The goal of this journal is to keep a record of the state-of-the-art research and to promote study, research and improvement within its various specialties. All manuscripts submitted to PP… All articles are open access under a CC BY 4.0 licence, with authors retaining copyright.
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