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Pharmacology & Pharmacy is a peer reviewed international journal dedicated to the latest advancements in Pharmacology & Pharmacy. The goal of this journal is to keep a record of the state-of-the-art research and to promote study, research and improvement within its various specialties. All manuscripts submitted to PP…
Taro Hihara, Kazuto Yamazaki, Tomohiko Taniguchi, Takashi Yoshinaga, Masashi Ito, Kohei Sawada
Drug-induced QT prolongation is a serious clinical issue in developing novel drug candidates and marketing drugs. A major cause of QT prolongation is direct inhibition of human ether-à-go-go -related gene (hERG) channels. Reduction in repolarization-related c…
Junshan Li, Bo Zhang
This study is aimed to validate the extraction process of Isatis Radix. Using near infrared spectroscopy and high performance liquid chromatography to determine the uridine, adenosine, guanosine contents in Isatis Radix Solution, as well as NIR to monitor the…
Yoshifumi Murata, Kyoko Kofuji, Norihisa Nishida, Ryosei Kamaguchi
Recently, potential applications for β -chitosan ( β -CS) have been examined. In the present study, calcium-induced alginate gel beads (Alg-Ca) containing weak acid salts of β -CS were prepared and examined with regard to their ability to adsorb bile acids in…
I. A. Iwara, G. O. Igile, I. P. Ogar, O. E. Mboso, U. P. Ujong, E. U. Eyong, P. E. Ebong
In this study, the anti-lipidemic effects of combined extracts of Moringa oleifera and Peristrophe bicalyculata in allxoan-induced diabetic rats were investigated. Fifty four (54) adult male albino Wistar rats weighing between 140-180 g were shared into 5 par…
Fiorenzo Santoleri, Paola Sorice, Ruggero Lasala, Alberto Costantini
Introduction: Liraglutide and Exenatide are used in adults who are affected by type-2 diabetes to control their blood glucose level. They are administered by the patients by subcutaneous injection, Liraglutide once a day while Exenatide twice a day. The aim o…
Lili Qu, Jiandong Jiang, Weijia Kong
3-Hydroxy-3-methylglutaryl coenzyme A (HMG-CoA) reductase inhibitors, or “statins”, are widely using cholesterol-lowering drugs with pleiotropic pharmacological effects. In this review, we summarized the pharmacological effects of statins related to gap junct…
Maud Kamatenesi Mugisha, James Gakunga Ndukui, Agnes Namutembi, Paul Waako, Ann-Karl Borg Karlson, Patrick Vudriko
Rumex abyssinica Jacq. (Polygonaceae ) is locally used in management of allergies and female re productive healthcare; whereas Mentha spicata L. (Lamiaceae) is used to treat gastrointestinal and respiratory distress, dandruff, halitosis and malaria in Uganda.…
Mohammad Al-Kaseem, Zaid Al-Assaf, François Karabeet
The present work reports a rapid reversed-phase high-performance liquid chromatography (RP-HPLC) method for the determination of seven volatile N-nitrosamines namely N-nitrosodi methylamine (NDMA), N-nitrosomethylethylamine (NMEA), N-nitrosodiethylamine (NDEA…
Mahmoud Taleb, Abed Al-Kareem Abed, Abedel Rahman Dahudi, Ahmed Najim, Adham Ahmed
Introduction: The increasing number of elderly, and drug use among the elderly, emphasizes the need for continuous monitoring of drug utilization. Chronic diseases are frequent among the older population ; the rate of drug related problems and drug-drug inter…
Hanan Polansky, Edan Itzkovitz
Objective: The Microcompetition with Foreign DNA theory, proposed by Hanan Polansky in 2003, describes how latent viruses can cause chronic conditions, including fatigue. The Gene-Eden-VIR formula was designed to target latent viruses. Therefore, the theory p…
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Pharmacology & Pharmacy is a peer reviewed international journal dedicated to the latest advancements in Pharmacology & Pharmacy. The goal of this journal is to keep a record of the state-of-the-art research and to promote study, research and improvement within its various specialties. All manuscripts submitted to PP… All articles are open access under a CC BY 4.0 licence, with authors retaining copyright.
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