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Pharmacology & Pharmacy is a peer reviewed international journal dedicated to the latest advancements in Pharmacology & Pharmacy. The goal of this journal is to keep a record of the state-of-the-art research and to promote study, research and improvement within its various specialties. All manuscripts submitted to PP…
Henry Nettey, Grace Lovia Allotey-Babington, Martin J. D’Souza
Sepsis is a host’s response to an intravascular infection; however, in most patients the disease recurs after a seemingly effective treatment. The reappearance of bacteria in the systemic circulation has been attributed to their ability to enter and hide with…
Hiroyoshi Kasai, Yumiko Aoyama, Takashi Kurasawa, Tomoyo Imamura, Kazuhiro Tsuruma, Hideaki Hara, Haruhisa Hirata, Tetsuya Yamamoto
Background: This study investigated the safety (cytotoxicity in vitro ) and pharmacological effects (ocular hypotensive effects and aqueous humor concentrations in normotensive monkeys in vivo ) of latanoprost formulations with benzalkonium chloride (latanopr…
Natalia Wszelaki, Matthias F. Melzig
Oxidative stress has been implicated as one of the cause s in cell death in many neurodegenerative disorders. Due to an tioxidative properties in vitro , the use of flavonoids and other polyphenolic compounds synthesised by plants are con sidered to be a prom…
Mouhssen Lahlou
Drug discovery leading to robust and viable lead candidates’ remains a challenging scientific task, which is the transition from a screening hit to a drug candidate, requires expertise and experience. Natural products and their derivatives have been recognize…
Shital Bhavin Butani
Purpose: Venlafaxine hydrochloride sustained release formulation increases patient compliance by reducing frequency of administration and it also reduces side effects like nausea and vomiting. Hence the objective of present investigation was to develop triple…
Steven J. Siegel, Lauren Nagy, Torben Skarsfeldt, Mark Pierce, Carol O’ Neill, Robert Lin, Lori Langhamer, Jeffery H. Kordower
Purpose: We compared efficacy and side effects of ropinirole implants with oral ropinirole in parkinsonian monkeys. Methods: Twenty monkeys received injections of 1-methyl-4-phenyl-1,2,3,6-tetrahydropyridine-hydrochloride (MPTP) to render them parkinsonian. M…
John D. Cleary, Kayla R. Stover, Jerry Farley, William Daley, Patrick B. Kyle, Jon Hosler
Cardiac toxicity is an uncommon side effect of anti-fungal therapy. Until the recent reports of itraconazole (ITZ) associated cardiac failure, amphotericin was the antifungal most frequently reported with arrhythmias. We evaluated the cardiac effect of azole…
Zakia Sultana, Md. Ershad Ali, Most. Afia Akhtar, Md. Sala Uddin, Md. Mominul Haque
Diabetes Mellitus is a leading cause of death in present world. This study was carried out to evaluate the management, control, complication profile and treatment strategies in patients with diabetes and to determine what extent management of diabetes in a te…
Mario I. Ortiz, Sandra Rivera-Roldán, Marco A. Escamilla-Acosta, Georgina Romo-Hernández, Héctor A. Ponce-Monter, Rita Escárcega-Ángeles
Background : The treatment used to combat acute lymphoblastic leukemia (ALL) is multidrug; therefore it is important to use active pharmacovigilance to detect, assess and analyze the likely adverse reactions which may occur during the same period. Objective:…
Hiroyuki Murakami, Toshiyuki Sakaeda, Kaori Kadoyama, Yasushi Okuno
Objective: The reports submitted to the US Food and Drug Administration (FDA) Adverse Event Reporting System (FAERS) from 1997 to 2011 were reviewed to assess the gender effects on muscular adverse events induced by the administration of 3-hydroxy-3-methylglu…
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Pharmacology & Pharmacy is a peer reviewed international journal dedicated to the latest advancements in Pharmacology & Pharmacy. The goal of this journal is to keep a record of the state-of-the-art research and to promote study, research and improvement within its various specialties. All manuscripts submitted to PP… All articles are open access under a CC BY 4.0 licence, with authors retaining copyright.
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