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Pharmacology & Pharmacy is a peer reviewed international journal dedicated to the latest advancements in Pharmacology & Pharmacy. The goal of this journal is to keep a record of the state-of-the-art research and to promote study, research and improvement within its various specialties. All manuscripts submitted to PP…
Lidia Serrano, Lorraine S. Decesar, Loan Pham
Head lice are a public health issue, and resistance to available over-the-counter pediculicides is a concern. The objective of this randomized study was to evaluate the pediculicidal activity and safety of 1% Sodium Chloride spray (0.1709 M), (LiceFreee Spray…
Toshimi Hattori, Keisuke Nakano, Toshiyuki Kawakami
Background: The mechanism concerning gingival overgrowth as a side effect of phenytoin, a therapeutic drug for epilepsy has been still unclear. As one of mechanisms, by measuring the intracellular calcium concentration ( [Ca 2+ ]i) of the gingival fibroblasts…
Tomoyasu Kamiya, Akira Takano, Yayoi Kido, Yuki Matsuzuka, Mayu Sameshima-Kamiya, Masahito Tsubata, Motoya Ikeguchi, Kinya Takagaki, Junei Kinjo
Pueraria flower extract (PFE) is a hot water extract of the Kudzu flower ( Pueraria thomsonii ). Tea made from dried Kudzu flower is widely used inChina, and PFE is utilized as a nutritional supplement inJapan. PFE contains unique isoflavones such as 6-hydrox…
Yuka Takasugi, Futoshi Kurai, Issei Kazume, Masaki Otsuka, Yoichi Negishi, Rui Tada, Yukihiko Aramaki
We have recently demonstrated that liposomes composed of phosphatidylserine (PS-liposomes) suppressed nitric oxide and inflammatory cytokine productions following LPS stimulation in macrophages. In this study, we examined the effect of PS-liposomes on express…
Justin J. Pettis, Stephanie R. Hyche, Katherine N. Logan, Arash Poursina, P. Brandon Bookstaver
Posaconazole, a triazole antifungal agent, displays a highly variable pharmacokinetic profile due in part to the oral solution, the only currently available dosage form. Posaconazole activity appears to be dose-dependent and clinical outcomes correlate with s…
Atsushi Kawase, Tetsuya Ohgami, Iho Yoshida, Yu Tsunokuni, Masahiro Iwaki
Nuclear receptors such as pregnane X receptor (PXR) and constitutive androstane receptor (CAR) regulate the transcription of transporter and cytochrome P450 (CYP). The diurnal variation was observed in some transporters regulated by nuclear receptors. We inve…
Dora Molina-Ortiz, José Francisco González-Zamora, Rafael Camacho-Carranza, Ocarol Lopez-Acosta, Oscar Colin-Martinez, Adriana Miriam Domínguez-Ramírez, Araceli Vences-Mejía
Cytochrome P450 (CYP) enzymes metabolize endogenous compounds such as steroid hormones, fatty acids, and xeno biotics, including drugs and carcinogens. The skeletal muscle is highly exposed to circulating xenobiotics; nevertheless the knowledge on the express…
Wasfi Asfour, Sawsan Almadi, Lina Haffar
Nigella sativa , belonging to the Ranunculacea family, is a versatile phytochemical mine bestowed with multi-dimen sional medicinal effects. The current study was performed to investigate the chemopreventive efficacy, if any, of the ethanolic extract of indig…
Federico Argüelles-Tello, Miriam del C. Carrasco-Portugal, Norma A. Carrasco-Portugal, José Carlos Aguilar-Carrasco, Selene I. Patiño-Camacho, Cecilia Fernández del Valle, Gerardo Reyes-Garcia, Francisco J. Flores-Murrieta
Clobenzorex is an anorexigenic drug that is widely used in Mexicofor the treatment of obesity, since it helps to reduce body weight. This drug is available as immediate release capsules. To improve compliance to treatment, it was devel oped a new slow release…
Sowmya Koppula, Mei-Chyi Tan, Angela Hurst, Caroline Telles, Wesley Gray
Low-level exposure to environmental pollutants such as BDO 2 contributes directly and indirectly to an increase in PCa. The aim of this study was to define the cellular changes associated with micro-doses of Butadiene Diepoxide (BDO 2 ) in prostate cancer cel…
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Pharmacology & Pharmacy is a peer reviewed international journal dedicated to the latest advancements in Pharmacology & Pharmacy. The goal of this journal is to keep a record of the state-of-the-art research and to promote study, research and improvement within its various specialties. All manuscripts submitted to PP… All articles are open access under a CC BY 4.0 licence, with authors retaining copyright.
Authors submit their manuscript, metadata, and declarations through the portal. There is no submission fee.
The editorial office screens the manuscript for scope, completeness, and formatting before assigning a handling editor.
At least two independent reviewers evaluate the manuscript under single-blind review. Where revisions are required, authors respond point by point.
On acceptance the article processing charge is invoiced and the CC BY 4.0 copyright handover is signed.
The article is copyedited, typeset, and given a DOI, then publishes open access with a permanent link.
Manuscripts must be original and not under consideration elsewhere. Submit in Microsoft Word or LaTeX with figures at 300 dpi minimum. Structure research articles as Abstract, Introduction, Methods, Results, Discussion, and References.
Use the journal's numbered (Vancouver) reference style. Cite sources consecutively in the order they appear, and ensure every reference is complete and retrievable.
Declare all funding sources, conflicts of interest, and ethical approvals (including informed consent and animal-care statements where applicable).