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Pharmacology & Pharmacy is a peer reviewed international journal dedicated to the latest advancements in Pharmacology & Pharmacy. The goal of this journal is to keep a record of the state-of-the-art research and to promote study, research and improvement within its various specialties. All manuscripts submitted to PP…
Mamdouh A .Z. Abu-Zaied, Galal A. M. Nawwar, Randa H. Swellem, Shahinaz H. El-Sayed
A series of newly 1,3,4-oxadiazole-2-thioglycoside derivatives were synthesized. The key step of this protocol is the coupling between 5-herteroaryl-1,3,4-oxadiazole-2-thione and activated sugars (cyclic or acyclic sugar analogues) in the presence of basic me…
Nicola Salvatore Orefice, Olga Ferraro, Francesco Barbato, Antonio Carotenuto, Roberta Lanzillo, Vincenzo Brescia Morra, Giovanni Coppola, Giuseppe Orefice
Multiple Sclerosis (MS) is a chronic inflammatory disease of the central nervous system (CNS) and is characterized by inflammation, demyelination and desctruction of oligodendrocytes and axons. The immunology of MS is complex, involving autoreactive Th1 and T…
Marion Wurr, Ingo Nolte, Dirk Stichtenoth
Atherosclerosis is the most prevalent disease in middle and later years of human life. Heart attacks and strokes are among the most frequent causes of death. New approaches in therapy are the use of NSAID’s (nonsteroidal antiphlogistical drugs) of the new gen…
Maria Leonarda De Rosa
Omega-3 ( ω -3) polyunsaturated fatty acids (PUFAs) from fish and fish oils appear to protect against coronary heart disease: their dietary intake is in fact inversely associated with cardiovascular disease morbidity/mortality in population studies. Recent ev…
Wenyu Qin, Bao He, Yu Bei, Rushang Wang, Lang Feng, Youhua Xu, Jiaxiao Zhu, Zhaoguang Zheng, Quan Zhu, Hong Nie
Advanced glycation end products (AGEs) have been regarded as a pivotal inducer in diabetes and kinds of diabetic nephropathy. The present studies explored the effects of Danggui Buxue Tang (DBT) that is a Chinese medicinal de- coction on negative charge to Hu…
Yao Potchoo, Edem Goe-Akue, Findibe Damorou, Barima Massoka, Datouda Redah, Innocent P. Guissou
High blood pressure (HBP) is a health problem world—wide. In Togo, that affection constitutes a more and more pre-occupying cause of morbidity and mortality. This study is a prospective one which intended to identify the antihypertensive regimens prescribed a…
Elias Adikwu, Nelson Brambaifa
Ciprofloxacin is generally well tolerated ; t he most common adverse effects include gastro intestinal tract, central nervous system and hematological system effects. Recently rising cases of Ciprofloxacin associated toxicity have been reported. Experiment us…
Toshihide Saito, Rinako Sawazaki, Kaori Ujiie, Masako Oda, Hiroshi Saitoh
Meropenem, a carbapenem antibiotic, is inactive after oral administration and administered exclusively by injection. In this study, in order to address the factors involved in the oral inactivity of meropenem, in vitro permeation characteristics across rat il…
Ping He, Jin-Yu Shen, Wen-Lin Yin, Jia-Yun Yao, Yang Xu, Xiao-Yi Pan, Gui-Jie Hao
Pharmacokinetics and residue elimination of streptomycin sulfate (STR) are important in the determination of optimal dosage regimens and in establishing safe withdrawal periods in farmed fishes. The pharmacokinetics of STR was studied after a single dose (50…
Debarshi Chakrabarti, Ashish Suthar, Gurunathan Jayaraman, Bhaskaran Muthuvelan, Somesh Sharma, Muralidhara Padigaru
Chronic inflammation induced hyper-proliferation, and migration of keratinocytes are pathological hallmarks of psoriasis. Extracts from Sphaeranthus spp. demonstrate pharmacological activity in-vitro and in-vivo . However, the activity in modulating disease r…
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Pharmacology & Pharmacy is a peer reviewed international journal dedicated to the latest advancements in Pharmacology & Pharmacy. The goal of this journal is to keep a record of the state-of-the-art research and to promote study, research and improvement within its various specialties. All manuscripts submitted to PP… All articles are open access under a CC BY 4.0 licence, with authors retaining copyright.
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