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Pharmacology & Pharmacy is a peer reviewed international journal dedicated to the latest advancements in Pharmacology & Pharmacy. The goal of this journal is to keep a record of the state-of-the-art research and to promote study, research and improvement within its various specialties. All manuscripts submitted to PP…
Humihisa Kanoh, Makiko Tada, Shinichi Ikushiro, Kiminori Mohri
Bucolome N-glucuronide (BCP-NG, main metabolite of bucolome (BCP) is the first N-glucuronide of barbituric acid derivatives isolated from rat bile. The objective of this study was to identify the main tissue producing BCP-NG and the molecular species of BCP-N…
Froylán Ibarra-Velarde, Cristina Guerrero-Molina, Yolanda Vera-Montenegro, Yazmín Alcalá-Canto, Evangelina Romero-Callejas
The aim of the present study was to evaluate the anthelmintic efficacy of three commercial compounds against ascarids and Capillaria spp. in naturally infected fighting cocks from Mexico. First experiment.- Forty cocks were selected on the basis of eggs per g…
Sevda Sasmaz, Ayse Saide Sahin, Ipek Duman
This in vitro study was designed to assess the effects of fentanyl on isolated rabbit thoracic aorta rings contracted with phenylephrine. Methods included contraction of aorta rings with phenylephrine (10<sup>–5</sup> M) and recording the changes after increa…
Updesh B Lade, Yogesh M Amgaonkar, Rupesh V Chikhale, Dinesh M Biyani, Milind J Umekar
Budesonide is a highly potent synthetic, nonhalogenated corticosteroid. The mechanism of action of corticosteroids in allergic rhinitis remains unknown, but may involve reductions in number of various mediator cells such as basophils, eosinophils, T-helper ce…
Yoshifumi Murata, Kyoko Kofuji, Norihisa Nishida, Ryosei Kamaguchi
We investigated preparation of film dosage form (FD) from natural polysaccharides using the casting method without organic solvents, heating or pH control. Ferulic acid (FA) and catechin were employed as model compounds incorporated in the FD, and the release…
Jun-lian Wang, Li Zhou, Lei Wang, Zheng hong Peng, Sheng ze Zhou, Xiang feng Zhou, Xiao bin Zhang, Bixian Peng
An attempt was made to establish a chromatographic separation and analysis method for capsaicinoids and their analogues. A series of factors,such as choice of column and eluents, eluent composition,flow rate of eluent and operational temperature were correlat…
Maura Lodovici, Elisabetta Bigagli, Cristina Luceri, Elena M Manni, Mohamed Zaid
We investigated the effect of resveratrol on oxidation damage and variation of antioxidant defences induced by 2-nitropropane (2-NP) in rat liver. One group of five rats was given resveratrol (50 mg/kg/d body weight) in the diet until the end of the experimen…
Chrysoula Spanou, Niki Tzioumaki, Stella Manta, Panagiotis Margaris, Dimitrios Kouretas, Dimitri Komiotis, Kalliopi Liadaki
Nucleoside analogues play an important role in the development of antitumor and antiviral agents. Specific sugar modified pyranonucleosides, like the keto and exocyclic methylene nucleosides, have been studied for their biological properties, but there is lit…
Gugliotta Tiziana, De Luca Grazia, Romano Pietro, Rigano Caterina, Romano Orazio, Scuteri Adriana, Romano Leonardo
The morphological and functional effects of titanium (Ti) citrate on human erythrocytes were studied by scanning electron microscope (SEM), sulphate uptake via band 3 protein and by determining the reduced and oxidised glutathione (GSH and GSSG, respectively)…
Jun-Lian WANG, Zheng-hong PENG, Sheng-ze ZHOU, Jin-xi Zhang, Song-fei Zhang, Xiang-feng ZHOU, Xiao-bin ZHANG, Bi-xian PENG
An attempt was made in an effort to synthesize a series of capsaicinoids, most of which are synthesized in our laboratory and characterized to be completely new members of capsaicinoids. The Structure-pungency dependence are presented and discussed.
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Pharmacology & Pharmacy is a peer reviewed international journal dedicated to the latest advancements in Pharmacology & Pharmacy. The goal of this journal is to keep a record of the state-of-the-art research and to promote study, research and improvement within its various specialties. All manuscripts submitted to PP… All articles are open access under a CC BY 4.0 licence, with authors retaining copyright.
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