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Pharmacology & Pharmacy is a peer reviewed international journal dedicated to the latest advancements in Pharmacology & Pharmacy. The goal of this journal is to keep a record of the state-of-the-art research and to promote study, research and improvement within its various specialties. All manuscripts submitted to PP…
Sara Rojas-Dotor, Liliana Vargas-Neri, Francisco Blanco-Favela
Apoptosis prevents the extravasation of intracellular material and the subsequent inflammatory response. Currently, it is not known whether Monocyte Locomotion Inhibitor Factor (MLIF), an anti-inflammatory pentapeptide, induces programmed cell death. We evalu…
Ken J. Grattendick, James M. Nakashima, Shri N. Giri
Tumor necrosis factor-alpha (TNF-α) is a potent inflammatory cytokine and its exaggerated production has been implicated in acute, chronic and autoimmune inflammatory diseases. Proteinaceous and non-proteinaceous anti-TNF-α agents have been developed to reduc…
Burak Cem Soner, Ayse Saide Sahin, Ipek Duman, Niyazi Gormus
<b>Aim</b>: Increased oxidative stress plays important roles in vascular dysfunction in patients undergoing coronary artery bypass graft surgery. Hydrogen peroxide (H<sub>2</sub>O<sub>2</sub>) is used as an experimental model for oxidative stress. The present…
Renu Chadha, Sushma Gupta, Natasha Pathak, Geeta Shukla, D.V.S. Jain, Raghuvir R S Pissurlenkar, Evans C Coutinho
The purpose of the present work is to improve the antimalarial activity of arteether through enhancing its solubility subsequently bioavailability by incorporating the drug into the cyclodextrins cavity. The effect of hydrophilic polyvinyl propylene (PVP) pol…
Rieko Takehira, Keiko Murakami, Sirou Katayama, Kenji Nishizawa, Shigeo Yamamura
Objective: With the goal of improving health-related quality of life (HRQOL) in cancer patients, we previously reported a structural equation model (SEM) of subjected QOL and qualifications of pharmacists, based on a series of questionnaires completed by pati…
Min-Jeong Kim, Ga-Young Lee, Yoo-Shin Park, Shin-Hee Kim, Sang-Yeon Kim, Mina Kang, Min-Ji Kim, Ju-Seop Kang
Our study compares two commonly used solutions of oxacillin sodium, 5.0 mg/mL in either 0.9% sodium chloride (NS) or 5% dextrose water (D5W), for their continued suitability for IV usage, and stability of active compound over time, when stored at two differen…
Shafir Botner, Amnon C. Sintov
Nasal application of benzodiazepines might be an alternative to intravenous administration in acute clinical situations such as seizures emergencies. However, irritation and pain as well as symptoms like teary eyes, dizziness, discomfort, nasal drainage and b…
Mikio Tomita, Rie Ohkubo, Shohei Ouchi, Chise Kawahata, Masahiro Hayashi
The mechanism of the nonlinear concentration dependence of the intestinal absorption of fluorescein isothiocyanate dextran 4,000 (FD-4) was studied using in situ rat intestinal loops and the in vitro Ussing-type chamber method. The intestinal absorption rate…
A Sivakumar, T.Panneer Selvam
The therapeutic value of Eugenia jambolana Lam. commonly known as ‘Jamun’ has been recognized in different system of traditional medication for the treatment of different diseases and ailments. It contains several phytoconstituents belonging to category of al…
Sunil Kumar Reddy Khambam, Madireddy Umamaheshwar Rao Naidu, Pingali Usha Rani, Takallapalli Ramesh Kumar Rao
In the present study, we evaluated laser Doppler flowmetry technique using LDF100C (Biopac systems) by determining blood flow changes following acute application of capsaicin on 12 healthy human subjects. Capsaicin applied locally (topical application) at a d…
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Pharmacology & Pharmacy is a peer reviewed international journal dedicated to the latest advancements in Pharmacology & Pharmacy. The goal of this journal is to keep a record of the state-of-the-art research and to promote study, research and improvement within its various specialties. All manuscripts submitted to PP… All articles are open access under a CC BY 4.0 licence, with authors retaining copyright.
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