Call for papersThe 2026 special issue on Climate & Health is open for submissions.Learn more
JCT is an international journal dedicated to the latest advancements in cancer therapy. The goal of this journal is to provide a platform for doctors and academicians all over the world to promote, share, and discuss various new issues and developments in cancer related problems. All manuscripts must be prepared in En…
Eva Gupta, Napoleon Santos, Yanxia Liu, Pamela Havre, Nam H. Dang, Hendrik Luesch, Long H. Dang
Epidermal growth factor receptor inhibitors have shown promise in the treatment of colorectal cancers. However, acti vating KRAS mutations cause primary resistance to these agents and contribute to cancer progression. Downstream signaling of oncogenic KRAS in…
Marjolaine Pelissier-Rota, Michèle Lainé, Benjamin Ducarouge, Bruno Bonaz, Muriel Jacquier-Sarlin
Inflammatory Bowel Disease (IBD) patients, such as Crohn ’ s disease or ulcerative colitis suffer from chronic and re lapsing intestinal inflammation that favours the development of colitis associated cancer (CAC). This inflammation is initiated by aberrant a…
Ergin Sahin, Michael E. Egger, Kelly M. McMasters, Heshan Sam Zhou
Reovirus, a double-stranded RNA virus, can infect many types of cancer cells and cause oncolysis. Mammalian reovirus has exhibited promising anticancer activity in clinical trials and holds great advantages and promise as an anticancer agent. Reovirus is not…
Leandro Nascimento de Oliveira, Flávia Vieira Guerra Alves, Paulo Alexandre Ribeiro Mora, Claudio Calazan do Carmo, Angélica Nogueira-Rodrigues, Alvaro Henrique Ingles Garces, Andréia Cristina de Melo
Objective: Cervical cancer represents the third most commonly diagnosed cancer and is an important cause of death for women suffering with malignancies. Patients who are refractory or progressed after first-line palliative treatment have a dismal prognosis an…
Isidoro Binda Neto, Samuel Marcos Ribeiro de Noronha, Silvana Aparecida Alves Correa de Noronha, Maria Del Carmen Garcia Molina Wolgien, Alexandre Jesus Barros, Clovis Ryiuchi Nakaie, Suma Imura Shimuta, Gil Facina, Ismael Dale Cotrim Guerreiro da Silva
Breast cancer is the most common cancer among women. Angiotensin-(1 - 7) [Ang-(1 - 7)] has been correlated with cancer antiproliferative and apoptotic effects, similar properties of the human Chorionic Gonadotrofin (hCG) . The aims of this work are to evaluat…
Silvana Aparecida Alves Corrêa de Noronha, Werica Bernardo, Alexandre Jesus Barros, Clovis Ryuichi Nakaie, Suma Imura Shimuta, Ismael Dale Cotrim Guerreiro da Silva, Samuel Marcos Ribeiro de Noronha
Angiotensin-(1 - 7) [Ang-(1 - 7)] is an endogenous heptapeptide hormone of the renin-angiotensin system that has anti proliferative properties. The aim of this work was to evaluate the anti-proliferative and pro-apoptotic properties of Ang-(1 - 7) and of Ang-…
Adelaide M. S. Antunes, Iolanda M. Fierro, Rafaela Di Sabato Guerrante, Priscila Rohem dos Santos, Flavia Maria Lins Mendes
Cancer is a leading cause of death worldwide, and is estimated to be the cause of 13.1 million deaths in 2030. Breast cancer is the second cancer in the global mortality ranking, considering both sexes. Due to the burden of breast cancer worldwide, this paper…
Claudia Gutiérrez Gómez, Anail Alvarez, Ana Lilia Ruelas, Ixchel Landgrave, Alfonso Vallarta, Laura Andrade
Recurrent eccrine syringomatous carcinoma is an extremely rare adnexal tumor predominantly found in the head and neck region. We present a case of a 75-year-old woman with a 7-year history of recurrent syringoid eccrine carcinoma in the scalp and auricle. She…
Kazuhiko Sato, Yoshio Mizuno, Hiromi Fuchikami, Masahiro Kato, Takahiro Shimo, Jun Kubota, Naoko Takeda, Yuko Inoue, Hiroshi Seto, Tomohiko Okawa
Background: Breast-conserving surgery (BCS) followed by whole breast irradiation (WBI) has become the standard of care for treating patients with early-stage breast cancer. Recently, various radiation techniques followed by BCS have been reported. We have bee…
Talaat Iman, Sorour Amani, Abdel-Hadi Mona
The accuracy of diagnostic assays for HER-2/neu in breast cancer is extremely important as HER-2/neu status is essen tial in tailoring adjuvant and /or neoadjuvant treatment in every patient. FNAC is widely practiced in Egypt in preopera tive diagnosis of bre…
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JCT is an international journal dedicated to the latest advancements in cancer therapy. The goal of this journal is to provide a platform for doctors and academicians all over the world to promote, share, and discuss various new issues and developments in cancer related problems. All manuscripts must be prepared in En… All articles are open access under a CC BY 4.0 licence, with authors retaining copyright.
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