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Call for papersThe 2026 special issue on Climate & Health is open for submissions.Learn more
JCT is an international journal dedicated to the latest advancements in cancer therapy. The goal of this journal is to provide a platform for doctors and academicians all over the world to promote, share, and discuss various new issues and developments in cancer related problems. All manuscripts must be prepared in En…
Bill E. Cham
Background: Untreated actinic keratosis can advance to squamous cell carcinoma, which in turn is associated with a risk of metastasis. Current treatments for actinic keratosis have many shortcomings. This communication describes the efficacy and safety of a t…
Carmine Cerullo, Carla Fonte, Andrea Muto, Agnese Vannini, Mattia Rediti, Sheila Rangan, Lorenzo Bordi, Bruno Neri
Glioblastoma multiforme (GBM) is the most malignant primary brain tumor. Conventional therapies are considered palliative and long-term progression-free survival remains low for most GBM patients even after surgical excision, concomitant radiotherapy and/or c…
Hideki Bou, Akira Tokunaga, Hideyuki Suzuki, Nobuo Murata, Yasuyuki Sugiyama, Naoto Fukuda, Masahiro Ishimaru, Hiroyuki Suzuki
Objective : The efficacy and safety of irinotecan hydrochloride (CPT-11) plus oral fluoropyrimidine S-1 combination therapy in patients with previously untreated advanced gastric cancer was evaluated. Methods: The regimen comprised CPT-11 plus S-1: CPT-11, 60…
Ling Gao, Xiaohua Chen, Zenghai Ma, Fengsheng Li
This article introduced the STYK 1 /NOK , including its origin, chemical composition and biological function, and the expression of STYK 1 /NOK in various cancer cell lines was reviewed. Furthermore, our recent study showed that STYK 1 /NOK protein was also o…
Tina Napso, Naiel Azzam, Aaron Lerner, Fuad Fares
N-myc downstream regulated gene 1 (NDRG1), also known as differentiation related gene 1, was previously identified as an up - regulated gene upon cellular differentiation. Even though its sequence along with its expressional pattern in cancer cell lines are e…
Nathan Tenley, David J. Corn, Lewis Yuan, Zhenghong Lee
The clinical utility of positron emission tomography (PET) imaging for liver cancer applications is not clearly defined either for diagnosis or treatment assessment. Previous clinical studies demonstrated that fluorodeoxyglucose (FDG) did not show uptake in s…
Justin I. Odegaard, Iris Schrijver
Hereditary diffuse gastric cancer is a rare, autosomal dominant hereditary cancer syndrome associated with germline mutations in CDH 1 in which 60% - 80% of affected individuals develop advanced diffuse gastric cancer, many as young adults. At clinical presen…
Yanxiang Cheng, Gantao Chen, Xiaohang Wang, Yuhui Huang, Jinli Ding, Jinling Huang, Li Hong
Ob jective: To explore what role the inflammatory immune response i s playing in the occurrence and development of HPV related cervical disease. Methods: To detect the expression of TLR4, HIF-1 α and HPV16 E7 in the specimens of HPV related cervical lesions,…
Sweta Sengupta, James Arocho, T. Christopher Windham
Introduction: The rate of squamous cell carcinoma spontaneous regression (SR) remains unknown because incidences are rare and underreported. Case Report: We present a case of a 92 - year-old Caucasian female who was found to have a 1 cm lesion on her nose. Pa…
Tamer Elbaz, Mohamed El Kassas, Gamal Esmat
Hepatocellular carcinoma (HCC) represents one of the most challenging potentially curable tumors with high incidence, prevalence and mortality rates. For proper assessment, prognosis estimation and treatment decisions, at least seven im portant guidelines and…
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JCT is an international journal dedicated to the latest advancements in cancer therapy. The goal of this journal is to provide a platform for doctors and academicians all over the world to promote, share, and discuss various new issues and developments in cancer related problems. All manuscripts must be prepared in En… All articles are open access under a CC BY 4.0 licence, with authors retaining copyright.
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The editorial office screens the manuscript for scope, completeness, and formatting before assigning a handling editor.
At least two independent reviewers evaluate the manuscript under single-blind review. Where revisions are required, authors respond point by point.
On acceptance the article processing charge is invoiced and the CC BY 4.0 copyright handover is signed.
The article is copyedited, typeset, and given a DOI, then publishes open access with a permanent link.
Manuscripts must be original and not under consideration elsewhere. Submit in Microsoft Word or LaTeX with figures at 300 dpi minimum. Structure research articles as Abstract, Introduction, Methods, Results, Discussion, and References.
Use the journal's numbered (Vancouver) reference style. Cite sources consecutively in the order they appear, and ensure every reference is complete and retrievable.
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