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Call for papersThe 2026 special issue on Climate & Health is open for submissions.Learn more
JCT is an international journal dedicated to the latest advancements in cancer therapy. The goal of this journal is to provide a platform for doctors and academicians all over the world to promote, share, and discuss various new issues and developments in cancer related problems. All manuscripts must be prepared in En…
Ofer Purim, Yulia Kundel, Roni Shapira, Baruch Brenner
Chemotherapy with continuous infusion of 5-fluorouracil and cisplatin in a monthly schedule is one of the most com mon regimens in the treatment of advanced gastric cancer. In this study, we evaluated the efficacy and safety of a dose dense administration of…
Shin-Ichiro Masunaga, Yoshinori Sakurai, Hiroki Tanaka, Minoru Suzuki, Natsuko Kondo, Masaru Narabayashi, Keizo Tano, Akira Maruhashi, Koji Ono
The aim in this study is to examine the effect of tirapazamine (TPZ) and mild temperature hyperthermia (MTH) on the repair of radiation-induced damage in pimonidazole-unlabeled quiescent (Q) tumor cells. Labeling of proliferating (P) cells in C57BL/6J mice be…
Mario Gosalvez
I present herewith a concise historic account of our development of the new technique for cancer therapy: Reversal of Cancer by Dual Strategy. This new method is based on the possible correction of the mitochondrial filamentation defect of tumors plus minor c…
Takashi Kosugi, Kazunori Suzuki, Kenta Konishi, Hotaka Nonaka, Hiroyuki Mineta
Purpose: To compare concurrent chemoradiotherapy with radiotherapy in T2N0 glottic cancer. Materials and Methods: Thirty nine patients were treated with radiotherapy alone. In detail, 30 patients treated between 1985 and 1995, and 9 patients treated between 1…
Huanjun Wang, Yan Guo, Xuhui Zhou, Dong Yang
Urinary bladder cancer is the second most common genitourinary malignancy in Westernized countries. A number of emerging imaging techniques have recently been reported in the literature for use in imaging bladder cancer. While the explicit application of MR i…
Wenfeng Huang
Tupistra chinensis is a widely used medicinal plant in Hubei Province ,China . In our study, we investigated the effect of polysaccharides component from Tupistra chinensis on mice in vivo . The mice H 22 hepatocarcinoma animal model was established firstly.…
Renumathy Dhanasekaran, Vinit Khanna, David A. Kooby, John S. Kauh, John D. Carew, Hyun S. Kim
Purpose: To investigate survival benefits and tumor treatment response among patients who received treatment with transarterial chemoembolization (TACE) combined with radiofrequency ablation (RFA) and TACE alone. Materials and Methods: A total of 108 HCC pati…
Soham Puvvada, Lisa Rimsza
This review discusses the impact of gene expression profiling and sequencing discoveries on new therapeutic strategies in Non-Hodgkin Lymphomas, particularly Diffuse Large B cell Lymphoma. Alterations in oncogenes, over-active signaling pathways down-stream o…
Yuko Watanabe, Hiroaki Suefuji, Etsuyo Ogo, Kensaku Sato, Tadashi Nakashima, Takashi Okamura, Koichi Ohshima, Naofumi Hayabuchi
Diffuse large B-cell lymphoma (DLBCL) is regarded as a heterogeneous group of lymphomas. The aims of this study were to determine the clinical significance and prognostic value of different immunophenotypic profiles in localized-stage head and neck DLBCL trea…
Kalman Szenthe, Katalin Nagy, Krisztina Buzas, Hans Helmut Niller, Janos Minarovits
MicroRNAs (miRNAs) are posttranscriptional regulators fine-tuning the level of most messenger RNAs (mRNAs) and proteins in mammalian cells. Their expression is dysregulated in neoplastic cells and upregulated or downregulated miRNAs play an important role in…
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JCT is an international journal dedicated to the latest advancements in cancer therapy. The goal of this journal is to provide a platform for doctors and academicians all over the world to promote, share, and discuss various new issues and developments in cancer related problems. All manuscripts must be prepared in En… All articles are open access under a CC BY 4.0 licence, with authors retaining copyright.
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