Call for papersThe 2026 special issue on Climate & Health is open for submissions.Learn more
JCT is an international journal dedicated to the latest advancements in cancer therapy. The goal of this journal is to provide a platform for doctors and academicians all over the world to promote, share, and discuss various new issues and developments in cancer related problems. All manuscripts must be prepared in En…
He Zuo, Huaidong Cheng
Radiotherapy (RT) remains a kind of front-line treatment for the control of tumor growth, especially for brain cancer. It is well known that cognitive impairment is mainly caused by cerebral RT, but the mechanisms underlying radiation-induced cognitive impair…
Yu Wang, Haishan Zhang, Yingxin Chen, Lining Wang
Lung cancer is one of the most prevalent cancers in the world. A cisplatin - based chemotherapy regimen is commonly used to major patients who have adenocarcinoma. Because of the limited remission rate, many patients need receive second-line treatment after r…
M. Nezami
In this paper we discuss the rationale of applying a “sequential” targeted therapy with a specific application in clinical practice, given our understanding of cancer heterogenous and dynamic biology. We explore the advantages of “single inhibition” to combin…
Conceição de Maria Lima Nascimento, Erenice Conceição de Almeida Barbosa, Brunna Rafaella Do Carmo Silva, Karoline Queiroz Martins Almeida de Araújo, Gilzandra Lira Dantas Florencio, Ana Carla Gomes Canário, Paulo Francisco de Almeida Neto, 1 1
Introduction : Hospital Recreation (HR) aims to reduce disasters caused by hospital admission. Objectives : To expose the behavior of children in cancer treatment (CA) during HR, and to verify which recreational activities generate the most adherence. Methods…
Wei Shi, Xinyue Wang, Xiwen Bi, Wen Xia, Jiajia Huang, Yanhong Su, Zhangzan Huang, Zhongyu Yuan
Purpose : Endocrine therapy is one of the main treatment options for hor mone receptor (HR)-positive advanced breast cancer (ABC). However, whether the combination of endocrine therapy with chemotherapy is practicable and more effective than endocrine therapy…
Miao Liu, Ai Shen, Wei Li, Lihui Chen, Xiufeng Chen, Hao Sun
Aim: To investigative the efficacy of carbon nanoparticles (CNs) to identify the lymph nodes during radical surgery in colorectal cancer. Method: The MEDLINE, EMBASE and Cochrane Library databases were searched electronically to identify the studies that comp…
Sacha Satram-Hoang, Preeti Bajaj, Alisha Stein, Patricia Cortazar, Faiyaz Momin, Carolina Reyes
Purpose : Triple negative breast cancer is more aggressive than other breast cancer subtypes and accounts for up to 20% of all breast cancer s . Despite the poorer prognosis, there are no approved targeted treatments available and chemotherapy remains the onl…
Yahia Ismail, Amr Kamal, Osama Yousof, Neveen Tahoun, Rasha Allam
Aim : Globally, primary adenocarcinoma (AC) accounts for only 0.5% - 2% of bladder cancer (BC). Bilharziasis predisposes to AC in ~10% of BC in endemic regions. The aim was to study the clinicopathologic characteristics of this rare entity and define prognost…
Aiat Morsy, Sara H. Hammouda, Samir Shehata
BACKGROUND Adjuvant radiotherapy is given following surgery in breast cancer patients. Hypofractonated radiotherapy can significantly reduce the waiting time for radiotherapy, working load on machines, patient visits to radiotherapy departments and medical co…
Onur Eroglu, Esin Guvenir Celik, Hacer Kaya, Merve Celen, Mustafa Karabicici, Elif Karacoban
Purpose: MCF-7 (ER+, WTP53) and MDA-MB-231 (ER Met, Mutant P53) Caffeic Acid Phenethyl Ester (CAPE) and DNA Methyl Transferase Inhibitor (DNMTi) in breast cancer cell lines of Zebularine (ZEB) single and combined application of TP53, caspase-9, caspase 8 and…
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JCT is an international journal dedicated to the latest advancements in cancer therapy. The goal of this journal is to provide a platform for doctors and academicians all over the world to promote, share, and discuss various new issues and developments in cancer related problems. All manuscripts must be prepared in En… All articles are open access under a CC BY 4.0 licence, with authors retaining copyright.
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