Call for papersThe 2026 special issue on Climate & Health is open for submissions.Learn more
JCT is an international journal dedicated to the latest advancements in cancer therapy. The goal of this journal is to provide a platform for doctors and academicians all over the world to promote, share, and discuss various new issues and developments in cancer related problems. All manuscripts must be prepared in En…
Christina Schröder, Eyck Blank, Dietrich Sidow, Rita Engenhart-Cabillic, André Buchali
Background and Purpose: There have been a number of different efforts trying to improve the outcome of NSCLC patients treated with radiotherapy (RT). Contrary to most expectations, the long awaiting results of the RTOG 0617 trial didn’t show any benefit of do…
Adnan Raza, Stephen Harden, Lukacs Veres, Khalid M. Amer
The aim of this case report is to raise awareness about the use of 3-Dimentional Computed Tomography (3D-CT) virtual reality imaging as a routine pre-operative tool for evaluation of unusual anatomy such as Situs Inversus Totalis (SIT). We present a case of p…
Danny V. Colombara, David Eidsmoe, Joshua E. Stern, Qinghua Feng, Hubert Vesselle, Stephen E. Hawes
p53 mutations have been linked with shortened survival rates in non-small cell lung cancer (NSCLC). Hypermethylation of RASSF1 and DAPK1 genes, which are downstream targets of p53, has also been linked to a poor prognosis in lung cancer patients. We investiga…
Ting Zhang, Weiguo Huang, 1 1
The competing endogenous RNA (ceRNA) hypothesis was introduced as a previously unrecognized gene regulatory layer. This is a recently discovered hypothesis about how mRNAs, pseudogene transcripts, long noncoding RNAs (lncRNAs) and circular RNAs (circRNAs) reg…
Sina Tok, Marian C. Neidert, Momen Sharab, I-Mei Siu, Jeanine P. Reyes, Vanessa Charubhumi, Robert T. Wicks, Charles Eberhart, George I. Jallo, Betty M. Tyler, 1 1, 1 1, 1 1
Background: We compared cutting and coagulation of a novel ferromagnetic tool (FMwand) with modalities currently used in the clinical setting. Methods: 24 F344 rats with 9L gliosarcoma flank tumours were randomized into 2 groups (n = 12): 1) Five parallel inc…
Masao Sugamata, Tomomi Ihara, Miho Sugamata
Since the mechanisms of the developmental processes of tumors remain unclear, early detection and early treatment of the tumors is necessary to save patients with malignant tumors. Therapies currently available to patients are surgery, chemotherapy, and radio…
Paul A. Oakley
Radiation hormesis is a concept that pervades radiobiological exposures; low doses enhance immune response, while higher doses inhibit immune response. Low-dose Total-Body Irradiation (TBI) therapy offers radiation treatment to cancer patients using the conce…
Xiuping Qian, Xiaolei Qian, Xinlin Chen, Mei Ge, Daijie Chen, Wenwei Mao
The efficacy of chemotherapy is thought to be direct killing of tumor cells, but documented studies have been shown that immunity plays a role in its effectiveness. In a pilot study to observe the bone marrow suppression and regeneration in tumor bearing mice…
Azza M. Nasr, Magda El Mongi, Mamdouh Hagag, Manar M. Moneer, Hisham El Hossieny, Azza Taher, Sherif Magdy
Purpose: Adjuvant radiation therapy could reduce loco regional failure, but currently has no defined role because of previously reported morbidity. NCI-Cairo routine work is to give adjuvant PORT for locally advanced bladder carcinoma patients. The aim of thi…
Mohamed Ben Mabrouk, Malek Barka, Waad Farhat, Fathia Harrabi, Mohamed Azzaza, Nefis Abdennaceur, Amine Schaidar, Abdelkader Mizouni, Jaafar Mazhoud, Ali Ben Ali
Studying in a retrospective review of 21 cases, diagnostic, therapeutic and evolutionary aspects of intra-abdominal cystic lymphangioma (CL). Methods: Between 1992 and 2014, 21 patients were operated at our institution for a CL. Clinical presentation, locatio…
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JCT is an international journal dedicated to the latest advancements in cancer therapy. The goal of this journal is to provide a platform for doctors and academicians all over the world to promote, share, and discuss various new issues and developments in cancer related problems. All manuscripts must be prepared in En… All articles are open access under a CC BY 4.0 licence, with authors retaining copyright.
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