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JDM is an international journal dedicated to the current developments of Diabetes Mellitus, the broad scope will also include significant research in the fields of pathology and therapeutic innovations of diabetes itself, both type I and II. All manuscripts submitted to JDM must be previously unpublished and may not b…
Subhashini Yaturu, Jared Davis, LaTonya Franklin, Runhua Shi, Prasanna Venkatesh, Sushil K. Jain
Background: Visceral adiposity correlates strongly with insulin resistance and components of metabolic syndrome. Visfatin is preferentially produced by human visceral adipose tissue. Objective: The objective of this study was to evaluate the relationship betw…
Victoria H. Tomlinson, Jane Langley, Andrew G. Meal, Gary G. Adams
Introduction: Critically ill patients can experience stress-induced hyperglycaemia. Glycaemic control therapy (GCT) is administered to control patients’ blood glycaemic levels and reduce the incidence of infection, myocardial infarctions and organ failure. Ho…
Yan Zhang, Youli Wang, Yunzi Chen, Dilip K. Deb, Tao Sun, Qun Zhao, Yan Chun Li
Renin is the rate-limiting enzyme of the reninangiotensin system (RAS). In addition to its enzymatic activity to generate angiotensin I, renin also signals through the (pro)renin receptor to exert angiotensin II-independent effects. In this study we examined…
Yuji Ishikawa, Takamichi Ito, Mitsuo Tanimoto, Shinji Hagiwara, Masako Furukawa, Saori Yamaguchi, Keisuke Omote, Katsuhiko Asanuma, Tomohito Gohda, Yoshio Shimizu, Kazuhiko Funabiki, Satoshi Horikoshi, Yasuhiko Tomino
Podocyte loss was well known in type 2 diabetic nephropathy patients. The objective of the present study was to determine the number of podocytes and the degree of albuminuria in diabetic KK-A y /Ta (KK-A y ) mice which had been reported as diabetic nephropat…
Kazunari Suzuki, Kentaro Watanabe, Tatsuya Suzuki, Motoshi Ouchi, Shoko Futami-Suda, Yoshimasa Igari, Hiroshi Nakano, Kenzo Oba
We evaluated the effect of sitagliptin on vascular endothelial function in Japanese type 2 diabetes patients without cardiovascular disease. Subjects included 24 Japanese type 2 diabetes patients without cardiovascular disease. This study was a prospective, o…
Ali Khan Khuwaja, Farzana Nawaz Ali, Imama Naqvi, Rasool Bux, Abdul Jabbar, Raheem Hassan Dhanani
Background: Metabolic syndrome (MS) is common among people with type 2 diabetes. The purpose of this study was to assess the proportion of MS and its individual components among type 2 diabetic adults, to stratify these by gender and to determine their associ…
Kenji Nishimura, Toshiaki Hirai, Shigeaki Nakazawa, Kazuaki Yamanaka, Hidefumi Kishikawa, Yasuji Ichikawa
Background: The purpose of this study was to determine whether the level of adiponectin in serum of renal transplant patients is associated with arterial stiffness related to new onset diabetes after transplantation (NODAT). Methods: A total of 90 previously…
Charles U. Osuji, Bernard A. Nzerem, Chudi E. Dioka, Samuel C. Meludu, Emmanuel I. Onwubuya
Background: For a long time Africa was considered safe from diabetes. However, the International Diabetes Federation predicts an increase in diabetes from 240 million in 2007 to 380 million in 2025 with 80% of the disease burden in low and middle-income count…
Goutameswar Mazumdar, Indranil Chakraborty, Bikash Swaika
Introduction: impaired glucose tolerance (IGT) often leads to type 2 diabetes (T2DM) and macro vascular disease; and usually associated with insulin resistance. Pioglitazone and metformin are commonly used insulin sensitizers (IS); and can prevent or delay th…
Eva Soelberg Vadstrup, A. Frølich, H. Perrild, E. Borg, M. Røder
Background: Today most guidelines on the management of type 2 diabetes incorporate lifestyle intervention including patient education, physical activity and dietary modification. However, the content and organization of lifestyle intervention programs are sti…
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JDM is an international journal dedicated to the current developments of Diabetes Mellitus, the broad scope will also include significant research in the fields of pathology and therapeutic innovations of diabetes itself, both type I and II. All manuscripts submitted to JDM must be previously unpublished and may not b… All articles are open access under a CC BY 4.0 licence, with authors retaining copyright.
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