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Open Journal of Immunology (OJI) is an international journal dedicated to the latest advancements in immunology. The goal of this journal is to provide a platform for scientists and academicians all over the world to promote, share, and discuss various new issues and developments in different areas of immunology. All…
Sivaram Gunisetty, Santosh Kumar Tiwari, Avinash Bardia, Meka Phanibhushan, Vishnupriya Satti, Mohammed Aejaz Habeeb, Aleem Ahmed Khan
Ulcerative colitis is considered frequent in majority of European and North American population and exceptional in most of the developing Asian countries. There is a dearth of reported data from South India on the incidence of the disease and its prevalence.…
Amanda Searle, Gene Scalarone
Diagnosis of blastomycosis is often done using a combination of clinical signs and cytologic or histopathologic identification of the organism, Blastomyces dermatitidis , from infected tissues. However, these methods are time consuming, invasive, and still le…
Abdel-Moneim M. Salim, Alaa B. Ismael
The present study was conducted mainly to establish a new concomitant immunity model to Schistosoma mansoni in mice and assess its effects on the resistance of mice to a challenge infection with a possibility of using as a diagnostic marker. Three groups (A,…
Bruna Daniella de Souza Silva, Sueli Lemes de Ávila Alves, André Kipnis, Ana Paula Junqueira-Kipnis
Introduction: Cutaneous tuberculosis (CTB) is a rare form of extra-pulmonary tuberculosis that, when associated with late diagnosis, worsen the quality of life of the sick individuals. This report presents a case of late diagnosis of CTB. Unusual clinical man…
Bolanle O. P. Musa, Geoffrey C. Onyemelukwe, Olubunmi A. Olatunji, Kingsley O. Odogwu, Joseph O. Hambolu, Terfa S. Kene
Background: Eclampsia, defined as the occurrence during pregnancy of hypertension, oedema, proteinuria and/or other neurologic abnormalities, causes substantial morbidity and mortality for both mother and foetus. However, its aetiology is largely unknown. Gen…
Eric L. Brown, Keri Csencsits Smith, Maria Gabriela Bowden
We previously observed the elicitation of a significant delayed-type hypersensitivity response to the Panton-Valentine leukocidin (PVL) LukS-PV subunit following subcutaneous immunization (Brown et al ., Clinical Microbiology and Infection , 2009, 156: 156-16…
Rebecca S. Thompson, Noor M. Khaskhely, Kristin R. Malhotra, David J. Leggat, Jason Mosakowski, Sadik Khuder, Gary R. McLean, M. A. Julie Westerink
Natural antibodies serve as the body’s first line of defense against pneumococcal challenge. Polyreactive human pneumococcal polysaccharide IgG antibodies have not been extensively studied. We analyzed human polyreactive antibodies that bind multiple pneumoco…
Pauline T. Lukey, Hayley C. Perry, Shuying Yang, Simon Parry, Marion C. Dickson, Virginia H. Norris, Paul G. Russell, Marie Watissée, Inmaculada Rioja, Keith P. Ray, Scott Crowe, Michael Binks
Purpose: To investigate the effects of single doses of losmapimod, dilmapimod (inhibitors of p38 MAPK) and prednisolone on biomarkers of systemic inflammation (serum C-reactive protein (CRP) and interleukin (IL)-6) in subjects with active rheumatoid arthritis…
Chi Chen, Praveen Kumar Yadav, Xingpeng Wang, Zhanju Liu
Defensins are endogenous antimicrobial peptides (AMPs) produced by professional phago- cytes, Paneth cells, and epithelial cells at mucosal surfaces, which mediate innate immunity through their potent antimicrobial activity in the intestinal tract. In additio…
Edith V. Bowers, Jennifer E. Bond, George J. Cianciolo, Salvatore V. Pizzo
Administered in vivo, covalent receptor-recognized α 2 -macroglobulin (α 2 M * )-antigen complexes enhance humoral and cell-mediated immunity. We hypothesized that in vivo α 2 M * -encapsulation could be promoted in the setting of vaccines that co-deliver α 2…
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Open Journal of Immunology (OJI) is an international journal dedicated to the latest advancements in immunology. The goal of this journal is to provide a platform for scientists and academicians all over the world to promote, share, and discuss various new issues and developments in different areas of immunology. All… All articles are open access under a CC BY 4.0 licence, with authors retaining copyright.
Authors submit their manuscript, metadata, and declarations through the portal. There is no submission fee.
The editorial office screens the manuscript for scope, completeness, and formatting before assigning a handling editor.
At least two independent reviewers evaluate the manuscript under single-blind review. Where revisions are required, authors respond point by point.
On acceptance the article processing charge is invoiced and the CC BY 4.0 copyright handover is signed.
The article is copyedited, typeset, and given a DOI, then publishes open access with a permanent link.
Manuscripts must be original and not under consideration elsewhere. Submit in Microsoft Word or LaTeX with figures at 300 dpi minimum. Structure research articles as Abstract, Introduction, Methods, Results, Discussion, and References.
Use the journal's numbered (Vancouver) reference style. Cite sources consecutively in the order they appear, and ensure every reference is complete and retrievable.
Declare all funding sources, conflicts of interest, and ethical approvals (including informed consent and animal-care statements where applicable).