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International Journal of Organic Chemistry (IJOC) is an international, specialized, English-language journal devoted to publication of original contributions concerning all field of organic chemistry. It is an open-access, peer-reviewed journal describing the synthetic approached and the design of new molecules for ap…
Mohammad Al-Masum, Baillie W. Lott, Nazanin Ghazialsharif
After purging air through the mixture of aldehydes and amino alcohols and microwaved the reaction mixture at 50°C for minutes gave the corresponding oxazinanes, and oxazolidines in excellent yields.
Nadia Ali Ahmed Elkanzi
A series of spiro, β -Lactams, and thiazolidinones incorporating compounds 4 have been synthesized by cycloaddition reaction of, chloroacetyl chloride and mercaptoacetic acid with the synthesized Shiff,s bases 5a-c to give new spiro β - Lactam 6a-c and spiro…
Abdel Haleem M. Hussein, Mohamed A. M. Gad-Elkareem, Abu-Bakr A. A. M. El-Adasy, Ahmed A. Khames, Ismail M. M. Othman
Condensation of β -Oxoanilide 1 with active methylene derivatives 2a,b afforded the pyridine derivative 5 , and with crotononitrile afforded the pyridine 8 . Compounds 9 and 11a-c were obtained by reaction of 1 with malononitrile dimer and arylidinemalononitr…
Kamatala Chinna Rajanna, Purugula Venkanna, Mukka Satish Kumar, Soma Ram Gopal
Sulfonation of aromatic compounds (Phenols, Anilines) is triggered by Vilsmeier Haack (VH) reagent (DMF/POCl 3 ) or (DMF/SOCl 2 ) in the presence of NaHSO 3 under Sonication and conventional stirred conditions at room temperature. The reactions afforded corre…
Jun-ichi Yamaguchi, Kanako Nozaki Abe, Takayuki Suyama
Diastereoselective conjugate addition of 1-enoyl-5-substituted hydantoins with allyltrimethylsilane in the presence of Ti(IV) chloride proceeded to give the corresponding allyl adducts in high yield and high diastereoselectivity. In order to determine the abs…
Wagnat W. Wardakhan, Sherif M. Sherif, Rafat M. Mohareb, Amr S. Abouzied
The reaction of cyanoacetylhydrazine 1 with furan-2-aldehyde 2 gives the hydrazide-hydrazone derivative 3 . The latter compound undergoes a series of heterocyclization reactions to give new heterocyclic compounds. The antitumor evaluation of the newly synthes…
Mohammed S. T. Makki, Dina A. Bakhotmah, Reda M. Abdel-Rahman, Mohammed S. El-Shahawy
A new biocidal agents fluorine substituted-3-thioxopyrimidine-5-carbonitriles ( 2-9 ) and/or the related fluorine substi- tuted pyrimido ( 4,5-d ) pyrimidines ( 10-14 ) were synthesized by the cycloaddition of fluorinated β- arylidine malo- nonitriles (1a-c)…
Suresh, Jagir S. Sandhu
A facile preparation of ZnO nanobelts by chemical precipitation technique and its utility as catalyst in Knoevenagel condensation of 2,4-thiazolidinedione/rhodanine has been described. X-ray diffraction and transmission electron microscopy techniques revealed…
Yui Ogasawara, Yuta Murai, Yasuko Sakihama, Yasuyuki Hashidoko, Makoto Hashimoto
The click reaction is one of the latest techniques for the functional analysis of bioactive compounds and the analysis makes novel concepts and strategies for medicinal chemistry. N -methylated glycine derivatives have inhibitory activity for the click reacti…
K. L. Ameta, Nitu S. Rathore, Biresh Kumar, Edith S. Malaga M, Manuela Verastegui P, Robert H. Gilman, B. L. Verma
Substituted 2-benzylidene-1-benzofuran-3-ones are commonly known as aurones. This class of bioactive heterocycles belongs to flavonoid family. The article intends to put forth the rational design and synthesis of a new series of aurones using 3’,5’-dibromo-2’…
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International Journal of Organic Chemistry (IJOC) is an international, specialized, English-language journal devoted to publication of original contributions concerning all field of organic chemistry. It is an open-access, peer-reviewed journal describing the synthetic approached and the design of new molecules for ap… All articles are open access under a CC BY 4.0 licence, with authors retaining copyright.
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