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International Journal of Organic Chemistry (IJOC) is an international, specialized, English-language journal devoted to publication of original contributions concerning all field of organic chemistry. It is an open-access, peer-reviewed journal describing the synthetic approached and the design of new molecules for ap…
Mohammed S. T. Makki, Dina A. Bakhotmah, Reda M. Abdel-Rahman
Highly efficient syntheses of novel fluorine bearing quinoline-4-carboxylic acids and the related compounds had been achieved from cyclocondensation of 2-amino-5-fluorophenyl glyoxylic acid 1 with benzoyle asetanilides 2 in boiling DMF, to give the target 3.…
Lokesh A. Shastri, Samundeeswari L. Shastri, Manohar V. Kulkarni, Vivek K. Gupta, Sanjeev Goswami
The present study reports the reaction of 4-bromomethylcoumarins with salicylidineaniline in acetone with two equivalents of potassium carbonate resulted in the formation of title compounds at room temperature via intramolecular aldolization. The obtained com…
Yutaka Okada, Daisuke Imanari
Rearrangements of the 1- and 2-cinnamyloxynaphthalenes undergo in diethylene glycol and decalin with solvent de-pendence. In 2-cinnamyloxynaphthalene, the Claisen rearrangement occurs regardless of the solvents. However, for the 1-analogue, the Claisen rearra…
Fatemeh Chadegani, Fatemeh Darviche, Saeed Balalaie
The one-pot three-component reaction of 2-aminobenzothiazole, benzaldehyde derivatives and β -ketoester, β -diketone or malonate derivatives in solvent-free conditions provides the corresponding pyrimido [2,1- b ] benzothiazole derivatives at 60?C in 60% - 72…
Miki Kanao, Atsushi Otake, Kousuke Tsuchiya, Kenji Ogino
Simple and efficient stereo-selective synthesis of exo -5-norbornene-2-carboxylic acid (NBCA) is reported. Preliminary studies on base promoted isomerization of methyl 5-norbornene-2-carboxylate (MNBC) revealed that rapid isomerization was accomplished with s…
Hengchang Ma, Zhikang Bao, Lianhua Bai, Wei Cao
Halogenated aluminates AlCl 3 , applied as efficient chlorination reagent for hydroxyl groups of substitution alcohols is described. Primary and secondary benzylic alcohols could be transformed into corresponding aromatic halides with almost complete conversi…
Ping An Wang, Hui Fang Nie, Lin Jie Yan, Sheng Yong Zhang
The novel well-defined chiral bicyclic thioureas based on enantiopure unsymmetric cis -2,5-disustituted pyrrolidine skeleton were firstly synthesized and fully characterized by their 1 H NMR, 13 C NMR and HRMS. Their absolute configurations were also determin…
Shahrzad Abdolmohammadi, Saeed Balalaie
A series of pyrido[2,3- d ]pyrimidines derivatives have been prepared by one-pot three-component reaction of 4(6)-aminouracil, malononitrile and aromatic aldehydes. This efficient synthesis was done under microwave irradiation conditions (method A) and also u…
Friederike M. Mansfeld, Istvan Toth
Endomorphin-1 is an endogenous opioid peptide that mediates pain relief through interaction with the μ-opioid receptor in the central nervous system. To enhance the metabolic stability of this tetrapeptide, cyclisation through the formation of a disulfide bri…
Zaman Ashraf, Aun Muhammad, Muhammad Imran, Ahmad Hussen Tareq
The work reports antibacterial and antifungal activity of different solvent extracts of Origanum vulgare. The antimicrobial activity of methanol, chloroform and aqueous extracts were determined against nine different gram negative and gram positive bacterial…
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International Journal of Organic Chemistry (IJOC) is an international, specialized, English-language journal devoted to publication of original contributions concerning all field of organic chemistry. It is an open-access, peer-reviewed journal describing the synthetic approached and the design of new molecules for ap… All articles are open access under a CC BY 4.0 licence, with authors retaining copyright.
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