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International Journal of Organic Chemistry (IJOC) is an international, specialized, English-language journal devoted to publication of original contributions concerning all field of organic chemistry. It is an open-access, peer-reviewed journal describing the synthetic approached and the design of new molecules for ap…
Angelbert F. Awantu, Yannick Stephane F. Fongang, Godfred A. Ayimele, Edouard A. Nantia, Patrick V. T. Fokou, Fabrice F. Boyom, Celine K. Ngwang, Bruno N. Lenta, Silvère A. Ngouela
Two novel Schiff bases, 3-[1-(2-(phthalazin-1-yl)hydrazono)ethyl)-1,3-oxa- zinane (PHEO) and 2-[(2-(phthalazin-1-yl)hydrazono)methyl]phenol (PHMP), derived from hydralazine hydrochloride, an effective drug against hypertension, were synthesized and characteri…
Shoichi Fukumoto, Miho Shigenobu, Kaori Ishimaru
Reaction of imines with 2-silyloxydiene catalyzed by ammonium chloride has been perfectly proceeded under environmentally friendly conditions to give Mannich-type product selectively. The reaction would proceed via Mannich-type mechanism, not cyclization/ring…
Olusegun B. Olubanwo, Arianna Kazez, Daniel W. Carney, Jason K. Sello
A new class of potential antibacterial agents has been synthesized on a new molecular scaffold of cyclohexane carboxylate. We have tagged this new class of compounds TACCs (Trisubstituted Aryl Cyclohexanecarboxylate). These new molecules are structural analog…
Abdullah Taha, Mahmood Amani
Oil and gas operations depend heavily on water in many different aspects. Water is present wherever there is hydrocarbon production. It is produced along with the hydrocarbons and helps in mobilizing them. It is also injected into the reservoirs to aid in mob…
Cosmas O. Okoro, Mumiye A. Ogunwale, Abiodun S. Oyedele
Xanthene and Xanthenediones are structural components of several bioactive and semi-synthetic molecules. This work described an expeditious synthesis of novel and hitherto unreported bis-trifluoromethyl xanthene dione derivatives. The reaction of two equivale…
Laila M. Break, Mosselhi A. M. Mohamed, Ohoud A. A. Al-Thubaiti, Fatma E. M. Eibaih
Pyrimidines, such as 6-amino-2-thio and 2-methylthiouracils and fused pyrimidines, such as thienopyrimidines reacted with 1- O -acetyl-2,3,5-tri- O - benzoyl- β -D-ribofuranose to get new derivatives of the corresponding nucleosides. The obtained protected nu…
Sydney N. Jackson, Rongson Pongdee
The construction of the C(1) - C(5) fragment of the resorcylic acid lactone pochonin J is described. The synthesis is marked by the installation of the cis-1,3-diol moiety in a highly stereoselective manner using Evans’ intra-molecular base-catalyzed oxyconju…
Reda M. Abdel Rahman, Abdulrahman S. Alharbi, Nawaa A. Alshammari
Novel 4-thiazolidione and 1,4-bis-thiazolidinone derivatives bearing antipyrine moiety have been obtained from condensation of 4-aminoantipyrine 1 with aromatic/heteroaldehydes followed by cycloaddition with mercaptoacetic acid in nonpolar solvents. Structure…
Dina A. Bakhotmah, Salwa Y. Al-Hazme
Novel heteropolycyclic nitrogen systems bearing fluorine substituted pyrazolo[3,4- d ] pyrimidine moiety have been synthesis by the interaction between N ’-heteroaryl guanidine 4 with polyfunctional π-acceptors in different media and condition. The structures…
Mohammed Al-Masum, Tasfia Islam, Grady Clopton
The direct aroylation of ArCOPdCl with potassium aryltrifluoroborates establishes a new cross-coupling synthetic tool for the synthesis of various fluorine substituted benzophenones. The new microwave irradiated process is very efficient and produce high yiel…
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International Journal of Organic Chemistry (IJOC) is an international, specialized, English-language journal devoted to publication of original contributions concerning all field of organic chemistry. It is an open-access, peer-reviewed journal describing the synthetic approached and the design of new molecules for ap… All articles are open access under a CC BY 4.0 licence, with authors retaining copyright.
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