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International Journal of Organic Chemistry (IJOC) is an international, specialized, English-language journal devoted to publication of original contributions concerning all field of organic chemistry. It is an open-access, peer-reviewed journal describing the synthetic approached and the design of new molecules for ap…
Hafsa Sayed, Dina A. Bakhotmah
In search for new antioxidant agents derived from 6-azauracil, the spiro-5-(flurin-9’-yl)-6-azauracil 3 and their N , N -disubstituted-6-azauracils 4 - 17 have been synthesized using various methods and reaction conditions. Structure of the new synthesized co…
Mohammad Al-Masum, Houra A. Alalwan
A mild, cascade type methodology was developed for the synthesis of polyphenolic ethers by the palladium-catalyzed cross coupling of phenols and halo compounds under microwave heating. In most cases, reactions run in neat conditions and in some cases, IPA/wat…
Clare E. Gutteridge, Brett W. Sadowski, Stephen M. Hughes, J. Alan Friedlander, Leighton G. Rodrigo, Michael C. Baxter, Nathan C. Lorei, Jonathan E. Harrell, Michael T. O’Neil
A versatile synthetic approach toward a series of benzothiazepines with medicinal potential (for example, compound 1 ) that allows incorporation of structural variation at the three aromatic regions of the structure, and at the sulfur atom, was developed. Kno…
Baktygul Ernazarova, Aida Bakirova, Asylkan Dzhumanazarova, Zhypargul Abdullaeva, Shamirbek Berkmamatov, Gulsara Zhusupbaeva
This work is describing a thionization method for glycosyl urea and carbamide of sugars by using the Lawesson’s reagent. It is proposed the method based on the interaction of glycosyl urea and carbamide of sugars with the Lawessons reagent at a 1:1 ratio in t…
Eman F. Kirolos, Amal S. Yanni
One pot criss-cross cycloaddition reaction of substituted 2,3-diaz-1,3-butadienes ( 1 ) and/or ( 2 ) with two equivalents of 2,3-dichloro-1,4-naphthoquinone in presence of dry benzene afforded bisnaphth[2,3-c]pyrazolidinetetrone derivatives ( 3 ) & ( 4 ). The…
Ali Bouattour, Mehdi Fakhfakh, Souhir Abid, Ludovic Paquin, Rémy Le Guével, Thierry Charlier, Sandrine Ruchaud, Stéphane Bach, Jean-Pierre Bazureau, Houcine Ammar
The synthesis of 2-phenylimino-4 H -chromene-3-carbonitriles 6(a-d) in good overall yields using an efficient and practical methodology in 3 steps has been implemented in this present work. The first step was a heterocyclization between 2-hydroxybenzaldehyde…
Abeer N. Al-Romaizan
In a search for new antimicrobial agents, some new spiro[indol-thiazolidon- 2,4-diones] ( 6a-c ) were synthesized by condensation of 5-substituted isatins 1 with sulfanilamide in MeOH, followed by aroylation with p-nitrobenzoyl chloride in DMF to get compound…
Wafa Bawazir
In this review a five-membered heterocyclic ring having two adjacent nitrogen atoms known as Pyrazole, we have framed 5-amino-N-substituted pyrazoles in particular focusing on its substantial role as a building block and starting materials for producing enorm…
Asmaa L. Alanzy, Dina A. Bakhotm, Reda M. Abdel-Rahman
The synthesis, preparation, chemical reactivities and biological activity of simple heterocyclic and heteropolycyclic nitrogen systems as small units as functional pyrazoles, pyridine and pyrimidine, and the related fused systems are reviewed. Among the vario…
Fatimah A. Alotaibi, Dina A. Bakhotmah
This overview summarizes recent advanced literature surveys on the synthesis of fluorine substituted 1,2,4-triazine containing various functional groups and/or the related hetero-polycyclic nitrogen systems have been reported. In addition, physical, chemical,…
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International Journal of Organic Chemistry (IJOC) is an international, specialized, English-language journal devoted to publication of original contributions concerning all field of organic chemistry. It is an open-access, peer-reviewed journal describing the synthetic approached and the design of new molecules for ap… All articles are open access under a CC BY 4.0 licence, with authors retaining copyright.
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