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Journal of Biophysical Chemistry (JBPC) is an international journal dedicated to the latest advancements in biophysical chemistry. The goal of this journal is to provide a platform for scientists and academicians all over the world to promote, share, and discuss various new issues and developments in different areas o…
Halina Abramczyk, Beata Brozek-Pluska, Jakub Surmacki, Joanna Jablonska-Gajewicz, Radzislaw Kordek
The paper presents the results for water confined in a human breast cancerous tissue, a single stranded DNA, a double stranded DNA and in phospholipids (DPPC - D-a-Phosphati dylcholine, dipalmitoyl). The interfacial water in DNA and lipids is represented by a…
Pankaj Hazarika, Bipul Bezbaruah, Pranjali Das, Okhil Kumar Medhi, Chitrani Medhi
The stacking of phenanthroline(phen) ligand within base pair sequences is one of the important factors for the stabilization of metalphen complex within DNA. The stacking ability of this ligand has been assessed to deduce the base pair selectivity as well as…
Lan-Ying Zhu, Guang-Qian Li, Fu-Yin Zheng
The interactions of bovine serum albumin (BSA) with two alkylimidazolium-based ionic liquids, 1-butyl-3-methylimidazolium tetrafluoroborate ([bmim]BF4) and 1-butyl-3-methylimidazolium hexafluorophosphate ([bmim]PF6), in buffer solutions at pH 7.0 were investi…
Jamie L. Kear, Luis Galiano, Angelo M. Veloro, Laura S. Busenlehner, Gail E. Fanucci
Site-directed spin-labeling with continuous wave electron paramagnetic resonance spectroscopy was used to monitor autoproteolysis of HIV-1 protease, an enzyme essential for viral maturation. Two protein constructs were examined, namely subtype F and the circu…
William N. Setzer
The epsilon class glutathione-S-transferase of <i>Anopheles gambiae</i>, agGSTe2, is capable of metabolizing DDT. A molecular docking analysis of DDT with agGSTe2 support an E2 elimination mechanism wherein the glutathione sulfur serves as the base to convert…
D. Balesh, Z. Ramjan, W.B. Floriano
Aggregation of alpha-synuclein leads to the formation of Lewy bodies in the brains of patients affected by Parkinson's disease (PD). Native human alpha-synuclein is unfolded in solution but assumes a partial alpha-helical conformation upon transient binding t…
Pradeep Kumar Naik, Piyush Ranjan, Pooja Kesari, Sankalp Jain
Given a protein sequence, how can we identify whether it is a metalloprotein or not? If it is, which main functional class and subclasses it belongs to? This is an important biological question because they are closely related to the biological function of an…
Hee-Bong Yoo, Hyuk-Min Lim, Inchul Yang, Sook-Kyung Kim, Sang-Ryoul Park
The degree and characteristics of physical degradation of macro-DNA molecules by common laboratory manipulations are reported. With linearized lambda-phage viral DNA as the model DNA, fragmentation of macro-DNA by various indispensable laboratory manipulation…
N. S. Al-Hokbany, R. M. Mahfouz, I. J. Al-Jammaz
A [ReO(Imz)(Hyd)(H<sub>2</sub>O)<sub>2</sub>OH] complex was successfully synthesized by the ligand exchange method using oxorhenuim citrate and an imidazole /Hydanton mixed ligand system. Geometry optimization of complex has been carried out using DFT at the…
M. R. Kabilov, D. V. Pyshnyi
Systematic analysis of factors determining efficiency in discrimination of a point substitution (SNP) within specific DNA sequences was carried out in the context of hybridization approach. There are two types of selectivity that are critical for the rational…
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Journal of Biophysical Chemistry (JBPC) is an international journal dedicated to the latest advancements in biophysical chemistry. The goal of this journal is to provide a platform for scientists and academicians all over the world to promote, share, and discuss various new issues and developments in different areas o… All articles are open access under a CC BY 4.0 licence, with authors retaining copyright.
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