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Call for papersThe 2026 special issue on Climate & Health is open for submissions.Learn more
JCT is an international journal dedicated to the latest advancements in cancer therapy. The goal of this journal is to provide a platform for doctors and academicians all over the world to promote, share, and discuss various new issues and developments in cancer related problems. All manuscripts must be prepared in En…
Gül Pınar, Ali Ayhan, Tevfik Pınar
Purpose: This study was conducted to describe emotional state of colostomized patients with gynecologic cancer. Pa tients and Methods: The study employed a qualitative design from May to October of 2010, in a private university hos pitals outpatient gnecologi…
Tohru Obata, Motohiro Tanaka, Yuka Suzuki, Takuma Sasaki
We established new pemetrexed-resistant cells originating from malignant pleural mesothelioma MSTO-211H cells to clarify the mechanism involved in pemetrexed resistance in malignant pleural mesothelioma. In the pemetrexed-resis tant cells, only thymidylate sy…
Luís Arthur Flores Pelloso, Sandra Serson Rohr, Mihoko Yamamoto, Maria de Lourdes L. F. Chauffaille
Granulocytic or myeloid sarcoma (MS) is a rare neoplastic condition consisting of a tumor mass of myeloid blasts with or without maturation occurring at an anatomical site other than the bone marrow the association between tuberculosis and MS is extremely rar…
Maria Grazia Ruggiero, Maria Laura Pollio, Antonietta Schiattarella, Antonella Borrelli, Aldo Mancini, Alessandra Pica, Patrizia Forgione
Physiological processes, as aerobic metabolism and inflammatory response, generate reactive oxygen species (ROS) that may induce cellular injury when their amount is increased and antioxidant defense mechanisms are overwhelmed. Also, ROS are generated followi…
Radik M. Khayrullin, Georgiy S. Terentyuk, Maria V. Savenkova, Elina A. Genina
Background: In recent years, worldwide attention of researchers focused on the practical implementation of nanoscale materials in biomedical technology. It’s p roved that intravenous injected gold nanoparticles are accumulated in tumor tis sues. However, when…
Yuanfu Qi, Xiurong Li, Huijie Li, Yi Zheng
Objective: To observe the effects and mechanisms of nanocrystallized realgar for the treatment of skin cancer. Methods: The clinical part was observing the therapeutic effect for the skin ulceration by externally using the nanocrystallized realgar. The experi…
Karen McGuire, James M. Jamison, Jacques Gilloteaux, Jack L. Summers
Exponentially growing cultures of human bladder tumor cells (RT4 and T24) were treated with Vitamin C (VC) alone, Vitamin K 3 (VK 3 ) alone, or with a VC:VK 3 combination continuously for 5 days or treated with vitamins for 1 h, washed with PBS and then incub…
Degui Wang, Siwei Ouyang, Yingxia Tian, Yan Yang, Bo Li, Xiangwen Liu, Yanfeng Song
Background: Histone deacetylase inhibitors (HDACI) are promising class of drugs acting as antiproliferative agents by promoting differentiation as well as inducing apoptosis. Vorinostat (suberoylanilide hydroxamic acid, SAHA) is the first among this new class…
Pedro Pimentel-Nunes, João Bruno Soares, Mário Dinis-Ribeiro
Toll-like receptors (TLR) are essential for Helicobacter pylori (Hp) recognition and subsequent innate and adaptive immunity responses. TLR2 appears to be the receptor responsible for most of the immunologic reaction against Hp in fection. However, TLR4, TLR9…
Fabrizio Romano, Fabio Uggeri, Luca Nespoli, Luca Gianotti, Mattia Garancini, Matteo Maternini, Angelo Nespoli, Franco Uggeri
Gastric adenocarcinoma is the third most common cancer and the second most common cause of death due to cancer worldwide. Surgery is still the major prognostic factor for gastric cancer. Patients who could not be resected have a poor prognosis with survival r…
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JCT is an international journal dedicated to the latest advancements in cancer therapy. The goal of this journal is to provide a platform for doctors and academicians all over the world to promote, share, and discuss various new issues and developments in cancer related problems. All manuscripts must be prepared in En… All articles are open access under a CC BY 4.0 licence, with authors retaining copyright.
Authors submit their manuscript, metadata, and declarations through the portal. There is no submission fee.
The editorial office screens the manuscript for scope, completeness, and formatting before assigning a handling editor.
At least two independent reviewers evaluate the manuscript under single-blind review. Where revisions are required, authors respond point by point.
On acceptance the article processing charge is invoiced and the CC BY 4.0 copyright handover is signed.
The article is copyedited, typeset, and given a DOI, then publishes open access with a permanent link.
Manuscripts must be original and not under consideration elsewhere. Submit in Microsoft Word or LaTeX with figures at 300 dpi minimum. Structure research articles as Abstract, Introduction, Methods, Results, Discussion, and References.
Use the journal's numbered (Vancouver) reference style. Cite sources consecutively in the order they appear, and ensure every reference is complete and retrievable.
Declare all funding sources, conflicts of interest, and ethical approvals (including informed consent and animal-care statements where applicable).